Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50030600
TargetStearoyl-CoA desaturase(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257967BDBM50257967(N-(2-(7-(4-chloro-3-(trifluoromethyl)benzylamino)-...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298907BDBM50298907(N-(2-(6-(3,4-dichlorobenzylamino)-3-oxo-2H-benzo[b...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257967BDBM50257967(N-(2-(7-(4-chloro-3-(trifluoromethyl)benzylamino)-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298907BDBM50298907(N-(2-(6-(3,4-dichlorobenzylamino)-3-oxo-2H-benzo[b...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298904BDBM50298904(2-hydroxy-N-(2-(2-oxo-3-(trifluoromethyl)-7-(3-(tr...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298904BDBM50298904(2-hydroxy-N-(2-(2-oxo-3-(trifluoromethyl)-7-(3-(tr...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298898BDBM50298898(2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluorometh...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257919BDBM50257919(N-(2-(7-(3,4-dichlorobenzylamino)-3-(4-methoxyphen...)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298909BDBM50298909(N-(2-(6-(3,4-dichlorobenzylamino)-2,2-dimethyl-3-o...)
Affinity DataIC50: 12nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298903BDBM50298903(1-(2-(3-methyl-2-oxo-7-(3-(trifluoromethyl)benzyla...)
Affinity DataIC50: 15nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257920BDBM50257920(N-(2-(3-(4-methoxyphenyl)-2-oxo-7-(3-(trifluoromet...)
Affinity DataIC50: 33nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298898BDBM50298898(2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluorometh...)
Affinity DataIC50: 38nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298902BDBM50298902((+/-)-2,3-dihydroxy-N-(2-(3-methyl-2-oxo-7-(3-(tri...)
Affinity DataIC50: 68nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298908BDBM50298908((+/-)-N-(2-(6-(3,4-dichlorobenzylamino)-2-methyl-3...)
Affinity DataIC50: 80nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257920BDBM50257920(N-(2-(3-(4-methoxyphenyl)-2-oxo-7-(3-(trifluoromet...)
Affinity DataIC50: 93nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257919BDBM50257919(N-(2-(7-(3,4-dichlorobenzylamino)-3-(4-methoxyphen...)
Affinity DataIC50: 110nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259177BDBM50259177(N-(3-(4-chloro-3-(trifluoromethyl)benzyl)-4-oxo-3,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259175BDBM50259175(N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50: 119nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298897BDBM50298897(N-(2-(3-methyl-2-oxo-7-(3-(trifluoromethyl)benzyla...)
Affinity DataIC50: 162nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259177BDBM50259177(N-(3-(4-chloro-3-(trifluoromethyl)benzyl)-4-oxo-3,...)
Affinity DataIC50: 190nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259175BDBM50259175(N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50: 261nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298902BDBM50298902((+/-)-2,3-dihydroxy-N-(2-(3-methyl-2-oxo-7-(3-(tri...)
Affinity DataIC50: 268nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298903BDBM50298903(1-(2-(3-methyl-2-oxo-7-(3-(trifluoromethyl)benzyla...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298901BDBM50298901(3-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluorometh...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298905BDBM50298905(2-hydroxy-N-(2-(3-isopropyl-2-oxo-7-(3-(trifluorom...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298906BDBM50298906(N-(2-(3-tert-butyl-2-oxo-7-(3-(trifluoromethyl)ben...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298900BDBM50298900((R)-2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluoro...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298899BDBM50298899((S)-2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluoro...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA 6-desaturase(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298898BDBM50298898(2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluorometh...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of stearoyl-CoA delta6 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Gilead Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298898BDBM50298898(2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluorometh...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of stearoyl-CoA delta5 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed