Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 50030845
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302559(N-(cis-4-{[4-(Dimethylamino)-5-methylpyrimidin-2-y...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302561(N-((cis)-4-(4-(dimethylamino)-5,6-dimethylpyrimidi...)
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302552(N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-...)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302555(N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-...)
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302569(3,5-dichloro-N-(((cis)-4-(4-(dimethylamino)-5-meth...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302553(3,4-dichloro-N-((cis)-4-(4-(dimethylamino)-6-methy...)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302568(N-[(cis-4-{[4-(Dimethylamino)-5-methylpyrimidin-2-...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50150715(4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethyla...)
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302557(N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302548(3-chloro-N-((cis)-4-(4-(dimethylamino)-6-methylpyr...)
Affinity DataIC50: 6.5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170191(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302551(N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-...)
Affinity DataIC50: 7.60nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302554(N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302546(N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-...)
Affinity DataIC50: 9.60nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170191(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 9.66nMAssay Description:Displacement of [125I]LSD from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302558(4-chloro-N-((cis)-4-(4-(dimethylamino)-5-methylpyr...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302556(N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302547(4-chloro-N-((cis)-4-(4-(dimethylamino)-6-methylpyr...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170191(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 16.9nMAssay Description:Inhibition of human 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302549(N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302565(N-(((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302555(N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-...)
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]rauwolsine from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302570(N-((cis)-4-(4-(ethyl(methyl)amino)-5-methylpyrimid...)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302562(N-((cis)-4-(4,6-bis(dimethylamino)pyrimidin-2-ylam...)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302567(3,5-dichloro-N-(((cis)-4-(4-(dimethylamino)-6-meth...)
Affinity DataIC50: 64nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302566(N-(((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2...)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302560(N-((cis)-4-(4-(dimethylamino)-5-ethylpyrimidin-2-y...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170191(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 104nMAssay Description:Displacement of [3H]MK-912 from human adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302564(N-(((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2...)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302556(N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-...)
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]rauwolsine from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302553(3,4-dichloro-N-((cis)-4-(4-(dimethylamino)-6-methy...)
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]MK-912 from human adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302553(3,4-dichloro-N-((cis)-4-(4-(dimethylamino)-6-methy...)
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]rauwolsine from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170191(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170191(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]rauwolsine from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302556(N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-...)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302547(4-chloro-N-((cis)-4-(4-(dimethylamino)-6-methylpyr...)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]rauwolsine from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302571(N-(((cis)-4-(5-methyl-4-(methylamino)pyrimidin-2-y...)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302554(N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-...)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]MK-912 from human adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302564(N-(((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2...)
Affinity DataIC50: 210nMAssay Description:Displacement of [3H]MK-912 from human adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302563(N-(((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2...)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302550(N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-...)
Affinity DataIC50: 230nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302558(4-chloro-N-((cis)-4-(4-(dimethylamino)-5-methylpyr...)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]rauwolsine from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302557(N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-...)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]rauwolsine from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170191(N-[4-(4-Dimethylamino-quinazolin-2-ylamino)-cycloh...)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]prazosin from human adrenergic alpha1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302568(N-[(cis-4-{[4-(Dimethylamino)-5-methylpyrimidin-2-...)
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]MK-912 from human adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302564(N-(((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2...)
Affinity DataIC50: 320nMAssay Description:Displacement of [3H]rauwolsine from human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302553(3,4-dichloro-N-((cis)-4-(4-(dimethylamino)-6-methy...)
Affinity DataIC50: 390nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302557(N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-...)
Affinity DataIC50: 470nMAssay Description:Displacement of [3H]MK-912 from human adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302555(N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-...)
Affinity DataIC50: 580nMAssay Description:Displacement of [3H]MK-912 from human adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302572(N-(((cis)-4-(4-amino-5-methylpyrimidin-2-ylamino)c...)
Affinity DataIC50: 600nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
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