Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50031186
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50308672(CHEMBL590070 | N-(Propylamide-benzophenone)-1-deox...)
Affinity DataIC50:  20nMAssay Description:Displacement of 4-methylumbelliferyl from non-lysosomal GBA2 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50308673(CHEMBL589341 | N-(Propylamide-acetophenone)-1-deox...)
Affinity DataIC50:  75nMAssay Description:Displacement of 4-methylumbelliferyl from non-lysosomal GBA2 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50308672(CHEMBL590070 | N-(Propylamide-benzophenone)-1-deox...)
Affinity DataIC50:  350nMAssay Description:Displacement of 4-methylumbelliferyl from human GBA by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50308673(CHEMBL589341 | N-(Propylamide-acetophenone)-1-deox...)
Affinity DataIC50:  1.65E+3nMAssay Description:Displacement of 4-methylumbelliferyl from human GBA by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  2.88E+4nMAssay Description:Displacement of 4-methylumbelliferyl from non-lysosomal GBA2 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  5.06E+5nMAssay Description:Displacement of 4-methylumbelliferyl from human GBA by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed