Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50041773
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335255BDBM50335255(3'-((2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-...)
Affinity DataEC50:  27.5nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147143BDBM50147143(2,2,2-trifluoro-N-(3-(pentan-2-yloxy)phenyl)-N-(py...)
Affinity DataEC50:  30.9nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415239BDBM50415239(CHEMBL593168)
Affinity DataEC50:  141nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415226BDBM50415226(CHEMBL594334)
Affinity DataEC50:  158nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393310BDBM50393310(CHEMBL605921)
Affinity DataEC50:  186nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415238BDBM50415238(CHEMBL606153)
Affinity DataEC50:  234nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415236BDBM50415236(CHEMBL595967)
Affinity DataEC50:  447nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415237BDBM50415237(CHEMBL595043)
Affinity DataEC50:  447nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415227BDBM50415227(CHEMBL612133)
Affinity DataEC50:  631nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415235BDBM50415235(CHEMBL595966)
Affinity DataEC50:  646nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415233BDBM50415233(CHEMBL594386)
Affinity DataEC50:  851nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415228BDBM50415228(CHEMBL607518)
Affinity DataEC50:  977nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415232BDBM50415232(CHEMBL595587)
Affinity DataEC50:  1.10E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415234BDBM50415234(CHEMBL593399)
Affinity DataEC50:  2.29E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415229BDBM50415229(CHEMBL593248)
Affinity DataEC50: >3.16E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415230BDBM50415230(CHEMBL593477)
Affinity DataEC50: >3.16E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50415231BDBM50415231(CHEMBL595586)
Affinity DataEC50: >3.16E+3nMAssay Description:Allosteric modulation of human mGluR2 expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed