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Found 80 Enz. Inhib. hit(s) with all data for entry = 50031188
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308710(3-{[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phe...)
Affinity DataIC50:  20nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308711(4-{[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phe...)
Affinity DataIC50:  20nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308712(5-(Phenylsulfonyl)-N-(1-{[3-(2H-tetrazol-5-yl)phen...)
Affinity DataIC50:  30nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308692(CHEMBL606033 | N-(1-{[6-(Dimethylamino)pyridin-3-y...)
Affinity DataIC50:  40nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308701(5-(Phenylsulfonyl)-N-{1-[(3S)-pyrrolidin-3-ylcarbo...)
Affinity DataIC50:  40nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308691(5-(Phenylsulfonyl)-2-(trifluoromethyl)-N-(1-{[6-(t...)
Affinity DataIC50:  50nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308698(CHEMBL600050 | tert-Butyl(3R)-3-{[4-({[5-(phenylsu...)
Affinity DataIC50:  50nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308702(5-(Phenylsulfonyl)-N-{1-[(3R)-pyrrolidin-3-ylcarbo...)
Affinity DataIC50:  60nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308688(5-(Phenylsulfonyl)-N-[1-(pyridin-3-ylcarbonyl)pipe...)
Affinity DataIC50:  60nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265500((S)-tert-butyl 2-(4-(5-(phenylsulfonyl)-2-(trifluo...)
Affinity DataIC50:  60nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308703(2-[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phen...)
Affinity DataIC50:  60nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308697(CHEMBL600049 | tert-Butyl(3S)-3-{[4-({[5-(phenylsu...)
Affinity DataIC50:  70nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308681(CHEMBL589088 | N-(1-Benzoylpiperidin-4-yl)-5-(phen...)
Affinity DataIC50:  70nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308689(CHEMBL589067 | N-(1-Isonicotinoylpiperidin-4-yl)-5...)
Affinity DataIC50:  80nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308713(CHEMBL592455 | N-{1-[(3-Cyanophenyl)sulfonyl]piper...)
Affinity DataIC50:  90nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308714(3-[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phen...)
Affinity DataIC50:  100nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308700(5-(Phenylsulfonyl)-N-[1-(piperidin-4-ylacetyl)pipe...)
Affinity DataIC50:  100nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265503((S)-5-(phenylsulfonyl)-N-(1-(pyrrolidine-2-carbony...)
Affinity DataIC50:  110nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308690(CHEMBL605196 | N-{1-[(6-Chloropyridin-3-yl)carbony...)
Affinity DataIC50:  110nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308699(5-(Phenylsulfonyl)-N-[1-(piperidin-4-ylcarbonyl)pi...)
Affinity DataIC50:  120nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308715(4-[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phen...)
Affinity DataIC50:  120nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265501((R)-tert-butyl 2-(4-(5-(phenylsulfonyl)-2-(trifluo...)
Affinity DataIC50:  120nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308716(5-(Phenylsulfonyl)-N-[1-(phenylsulfonyl)piperidin-...)
Affinity DataIC50:  130nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308694(CHEMBL590478 | N-{1-[(6-Morpholin-4-ylpyridin-3-yl...)
Affinity DataIC50:  130nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308704(CHEMBL591483 | [4-({[5-(Phenylsulfonyl)-2-(trifluo...)
Affinity DataIC50:  190nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308682(CHEMBL589331 | N-[1-(2-Chlorobenzoyl)piperidin-4-y...)
Affinity DataIC50:  200nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308687(5-(Phenylsulfonyl)-N-[1-(pyridin-2-ylcarbonyl)pipe...)
Affinity DataIC50:  200nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265504((R)-5-(phenylsulfonyl)-N-(1-(pyrrolidine-2-carbony...)
Affinity DataIC50:  200nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308709(CHEMBL602239 | N-[1-(2-Hydroxy-2-methylpropyl)pipe...)
Affinity DataIC50:  200nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308706(4-Oxo-4-[4-({[5-(phenylsulfonyl)-2-(trifluoromethy...)
Affinity DataIC50:  270nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308695(CHEMBL590304 | tert-Butyl 4-{[4-({[5-(phenylsulfon...)
Affinity DataIC50:  300nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308686(CHEMBL589567 | N-{1-[4-(Dimethylamino)benzoyl]pipe...)
Affinity DataIC50:  300nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308684(CHEMBL590541 | N-[1-(4-Chlorobenzoyl)piperidin-4-y...)
Affinity DataIC50:  300nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308683(CHEMBL589332 | N-[1-(3-Chlorobenzoyl)piperidin-4-y...)
Affinity DataIC50:  300nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308685(5-(Phenylsulfonyl)-2-(trifluoromethyl)-N-{1-[4-(tr...)
Affinity DataIC50:  400nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308696(CHEMBL590312 | tert-Butyl 4-{2-oxo-2-[4-({[5-(phen...)
Affinity DataIC50:  490nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308708(CHEMBL592692 | N-[1-(2-Hydroxyethyl)piperidin-4-yl...)
Affinity DataIC50:  500nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308707(5-Oxo-5-[4-({[5-(phenylsulfonyl)-2-(trifluoromethy...)
Affinity DataIC50:  500nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308693(5-(Phenylsulfonyl)-N-{1-[(6-pyrrolidin-1-ylpyridin...)
Affinity DataIC50:  870nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308705(3-[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phen...)
Affinity DataIC50:  900nMAssay Description:Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308693(5-(Phenylsulfonyl)-N-{1-[(6-pyrrolidin-1-ylpyridin...)
Affinity DataEC50:  230nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308694(CHEMBL590478 | N-{1-[(6-Morpholin-4-ylpyridin-3-yl...)
Affinity DataEC50:  140nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308695(CHEMBL590304 | tert-Butyl 4-{[4-({[5-(phenylsulfon...)
Affinity DataEC50:  420nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308696(CHEMBL590312 | tert-Butyl 4-{2-oxo-2-[4-({[5-(phen...)
Affinity DataEC50:  400nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265500((S)-tert-butyl 2-(4-(5-(phenylsulfonyl)-2-(trifluo...)
Affinity DataEC50:  60nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265501((R)-tert-butyl 2-(4-(5-(phenylsulfonyl)-2-(trifluo...)
Affinity DataEC50:  210nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308697(CHEMBL600049 | tert-Butyl(3S)-3-{[4-({[5-(phenylsu...)
Affinity DataEC50:  150nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308698(CHEMBL600050 | tert-Butyl(3R)-3-{[4-({[5-(phenylsu...)
Affinity DataEC50:  80nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308699(5-(Phenylsulfonyl)-N-[1-(piperidin-4-ylcarbonyl)pi...)
Affinity DataEC50:  150nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308700(5-(Phenylsulfonyl)-N-[1-(piperidin-4-ylacetyl)pipe...)
Affinity DataEC50:  210nMAssay Description:Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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