Compile Data Set for Download or QSAR
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Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50031431
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50303054((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N6-(5-met...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant JAK2 kinase in presence of 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50313159((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-met...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant JAK2 kinase in presence of 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50313162((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N6-(5-met...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant JAK2 kinase in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50313157((S)-N2-(1-(5-fluoropyridin-2-yl)ethyl)-N4-(5-methy...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant JAK2 kinase in presence of 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50313162((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N6-(5-met...)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant JAK2 kinase in presence of 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50313157((S)-N2-(1-(5-fluoropyridin-2-yl)ethyl)-N4-(5-methy...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50313160((S)-N2-(1-(5-fluoropyridin-2-yl)ethyl)-6-(4-methyl...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50313161((S)-2-(2-(1-(5-fluoropyridin-2-yl)ethylamino)-6-mo...)
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50313159((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-met...)
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50313158((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-6-methoxy...)
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50303054((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N6-(5-met...)
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed