Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50039055
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50131550((3S)-3-{[(1S)-1-carbamoyl-2-{4-[difluoro(phosphono...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50131550((3S)-3-{[(1S)-1-carbamoyl-2-{4-[difluoro(phosphono...)
Affinity DataKi:  24nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataKi:  1.64E+5nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307997(2-(2-Carboxy-benzoylamino)-4-(30-chloro-40-fluorob...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307999(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-5-methy...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307995(2-(2-Carboxy-benzoylamino)-4-(40-methoxy-biphenyl-...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307994(2-(2-Carboxy-benzoylamino)-4-(30-methoxy-biphenyl-...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307996(2-(2-Carboxy-benzoylamino)-4-(40-fluoro-biphenyl-4...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307997(2-(2-Carboxy-benzoylamino)-4-(30-chloro-40-fluorob...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307992(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-thiophe...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307990(2-[(3-Carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307997(2-(2-Carboxy-benzoylamino)-4-(30-chloro-40-fluorob...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307990(2-[(3-Carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307999(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-5-methy...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50:  8.00E+3nMAssay Description:Allosteric inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307993(2-(2-Carboxy-benzoylamino)-4-(20-methoxy-biphenyl-...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307998(4-Biphenyl-3-yl-2-(2-carboxy-benzoylamino)-thiophe...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307999(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-5-methy...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 2A activator(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307997(2-(2-Carboxy-benzoylamino)-4-(30-chloro-40-fluorob...)
Affinity DataIC50:  2.31E+4nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307991(2-[(3-Carboxy-bicyclo[2.2.1]heptane-2-carbonyl)-am...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307990(2-[(3-Carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)...)
Affinity DataIC50:  3.26E+4nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307999(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-5-methy...)
Affinity DataIC50:  4.86E+4nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 2A activator(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307999(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-5-methy...)
Affinity DataIC50:  4.97E+4nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50:  6.67E+4nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 2A activator(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307997(2-(2-Carboxy-benzoylamino)-4-(30-chloro-40-fluorob...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 2A activator(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307990(2-[(3-Carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 2A activator(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307990(2-[(3-Carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed