Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50039055
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131550BDBM50131550((S)-4-((S)-1-amino-3-(4-(difluoro(phosphono)methyl...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131550BDBM50131550((S)-4-((S)-1-amino-3-(4-(difluoro(phosphono)methyl...)
Affinity DataKi:  24nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307997BDBM50307997(2-(2-Carboxy-benzoylamino)-4-(30-chloro-40-fluorob...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308000BDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307999BDBM50307999(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-5-methy...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307995BDBM50307995(2-(2-Carboxy-benzoylamino)-4-(40-methoxy-biphenyl-...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307994BDBM50307994(2-(2-Carboxy-benzoylamino)-4-(30-methoxy-biphenyl-...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307996BDBM50307996(2-(2-Carboxy-benzoylamino)-4-(40-fluoro-biphenyl-4...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307997BDBM50307997(2-(2-Carboxy-benzoylamino)-4-(30-chloro-40-fluorob...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307992BDBM50307992(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-thiophe...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307990BDBM50307990(2-[(3-Carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307989BDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307997BDBM50307997(2-(2-Carboxy-benzoylamino)-4-(30-chloro-40-fluorob...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307990BDBM50307990(2-[(3-Carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13990BDBM13990(CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307999BDBM50307999(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-5-methy...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308000BDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50: 8.00E+3nMAssay Description:Allosteric inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307993BDBM50307993(2-(2-Carboxy-benzoylamino)-4-(20-methoxy-biphenyl-...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307998BDBM50307998(4-Biphenyl-3-yl-2-(2-carboxy-benzoylamino)-thiophe...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307999BDBM50307999(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-5-methy...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308000BDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307997BDBM50307997(2-(2-Carboxy-benzoylamino)-4-(30-chloro-40-fluorob...)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307991BDBM50307991(2-[(3-Carboxy-bicyclo[2.2.1]heptane-2-carbonyl)-am...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307990BDBM50307990(2-[(3-Carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)...)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307989BDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307989BDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307999BDBM50307999(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-5-methy...)
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307999BDBM50307999(4-Biphenyl-4-yl-2-(2-carboxy-benzoylamino)-5-methy...)
Affinity DataIC50: 4.97E+4nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308000BDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50: 6.67E+4nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307990BDBM50307990(2-[(3-Carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307989BDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307989BDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307990BDBM50307990(2-[(3-Carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 2A activator(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308000BDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308000BDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307997BDBM50307997(2-(2-Carboxy-benzoylamino)-4-(30-chloro-40-fluorob...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13990BDBM13990(CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...)
Affinity DataKi:  1.64E+5nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed