Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50032325
TargetDihydrofolate reductase(Human)
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program

Curated by ChEMBL
LigandPNGBDBM18793(6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]...)
Affinity DataKi:  7.70nMAssay Description:Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program

Curated by ChEMBL
LigandPNGBDBM50035483(5-Chloro-N*6*-(2,5-dimethoxy-benzyl)-quinazoline-2...)
Affinity DataKi:  10.2nMAssay Description:Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program

Curated by ChEMBL
LigandPNGBDBM18512(cid_4993 | CHEMBL36 | 5-(4-chlorophenyl)-6-ethylpy...)
Affinity DataKi:  30.8nMAssay Description:Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program

Curated by ChEMBL
LigandPNGBDBM18792(Chlorazin | 1-(4-chlorophenyl)-6,6-dimethyl-1,6-di...)
Affinity DataKi:  55.6nMAssay Description:Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed