Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50032328
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327206((2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-ind...)
Affinity DataKd:  75nMAssay Description:Binding affinity to Hdm2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327206((2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-ind...)
Affinity DataKd:  75nMAssay Description:Binding affinity to Hdm2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327206((2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-ind...)
Affinity DataKd:  390nMAssay Description:Binding affinity to MDMXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327206((2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-ind...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327206((2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-ind...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GST-tagged p53 binding to Hdm2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327208(tert-butyl (S)-1-((S)-1-((S)-3-(1H-indol-3-yl)-1-o...)
Affinity DataIC50: 1.92E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327213((3S,6S,9S,12S,15S,18S)-3-benzyl-6-sec-butyl-15,18-...)
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of GST-tagged p53 binding to Hdm2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327210(isobutyl (6S,9S,12S)-9-((1H-indol-3-yl)methyl)-1-a...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327209((4S,7S,10S)-7-((1H-indol-3-yl)methyl)-15-amino-4-b...)
Affinity DataIC50: 3.07E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327211(tert-butyl (6S,9S,12S)-9-((1H-indol-3-yl)methyl)-1...)
Affinity DataIC50: 3.39E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327212(benzyl (6S,9S,12S)-9-((1H-indol-3-yl)methyl)-1-ami...)
Affinity DataIC50: 3.48E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327207(((S)-5-((S)-3-(1H-indol-3-yl)-1-oxo-1-((S)-1-oxo-3...)
Affinity DataIC50: 4.63E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed