Compile Data Set for Download or QSAR
Report error Found 70 Enz. Inhib. hit(s) with all data for entry = 50032672
LigandChemical structure of BindingDB Monomer ID 50333027BDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 360nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333031BDBM50333031(4-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163188...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333028BDBM50333028(3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333017BDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333027BDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333031BDBM50333031(4-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163188...)
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333016BDBM50333016(3-(Pyridin-2-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333024BDBM50333024(3-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333024BDBM50333024(3-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50: 5.12E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333016BDBM50333016(3-(Pyridin-2-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333017BDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333016BDBM50333016(3-(Pyridin-2-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333027BDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333031BDBM50333031(4-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163188...)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333024BDBM50333024(3-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333027BDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333017BDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333028BDBM50333028(3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333025BDBM50333025(3-(Pyridin-2-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333027BDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333031BDBM50333031(4-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163188...)
Affinity DataIC50: 3.92E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333027BDBM50333027(3-(Pyridin-4-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333018BDBM50333018(4-((1H-Indazol-3-yl)ethynyl)benzonitrile | CHEMBL1...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333021BDBM50333021(2-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333030BDBM50333030(3-(Phenylethynyl)-1H-indazole | CHEMBL1631889)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333016BDBM50333016(3-(Pyridin-2-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333017BDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333026BDBM50333026(3-(1H-Indazol-3-yl)-N,N-dimethylprop-2-yn-1-amine ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333028BDBM50333028(3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333030BDBM50333030(3-(Phenylethynyl)-1H-indazole | CHEMBL1631889)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333022BDBM50333022(3-(Cyclopropylethynyl)-1H-indazole | CHEMBL1631897)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333023BDBM50333023(3-(Cyclopentylethynyl)-1H-indazole | CHEMBL1631896)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333026BDBM50333026(3-(1H-Indazol-3-yl)-N,N-dimethylprop-2-yn-1-amine ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333025BDBM50333025(3-(Pyridin-2-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333020BDBM50333020(3-((3,5-Bis(trifluoromethyl)phenyl)ethynyl)-1Hinda...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333021BDBM50333021(2-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333022BDBM50333022(3-(Cyclopropylethynyl)-1H-indazole | CHEMBL1631897)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333023BDBM50333023(3-(Cyclopentylethynyl)-1H-indazole | CHEMBL1631896)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333018BDBM50333018(4-((1H-Indazol-3-yl)ethynyl)benzonitrile | CHEMBL1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333019BDBM50333019(3-(Thiophen-3-ylethynyl)-1H-indazole | CHEMBL16319...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333028BDBM50333028(3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333029BDBM50333029(3-((3,5-Difluorophenyl)ethynyl)-1H-indazole | CHEM...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333030BDBM50333030(3-(Phenylethynyl)-1H-indazole | CHEMBL1631889)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333024BDBM50333024(3-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333025BDBM50333025(3-(Pyridin-2-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333026BDBM50333026(3-(1H-Indazol-3-yl)-N,N-dimethylprop-2-yn-1-amine ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333020BDBM50333020(3-((3,5-Bis(trifluoromethyl)phenyl)ethynyl)-1Hinda...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333019BDBM50333019(3-(Thiophen-3-ylethynyl)-1H-indazole | CHEMBL16319...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333021BDBM50333021(2-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163189...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50333020BDBM50333020(3-((3,5-Bis(trifluoromethyl)phenyl)ethynyl)-1Hinda...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
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