Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 8162
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235646BDBM235646(Hydroxyethylamine (HEA))
Affinity DataIC50: 49nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235642BDBM235642((E)-1-(2,4-dihydroxyphenyl)-3-(2,3-dihydroxyphenyl...)
Affinity DataIC50: 270nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 50203985BDBM50203985(2,2',4,4'-tetrahydroxychalcone | 2,4,2',4'-tetrahy...)
Affinity DataIC50: 620nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235644BDBM235644((E)-1-(2,4-dihydroxyphenyl)-3-(2,6-dihydroxyphenyl...)
Affinity DataIC50: 1.71E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235643BDBM235643((E)-1-(2,4-dihydroxyphenyl)-3-(2,5-dihydroxyphenyl...)
Affinity DataIC50: 1.94E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235645BDBM235645((E)-1-(2,4-dihydroxyphenyl)-3-(3,5-dihydroxyphenyl...)
Affinity DataIC50: 2.08E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 50042949BDBM50042949((E)-3-(3,4-Dihydroxy-phenyl)-1-(2,4-dihydroxy-phen...)
Affinity DataIC50: 2.37E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 50027475BDBM50027475(2,2'',4''-Trihydroxychalcone | CHEMBL148472 | (E)-...)
Affinity DataIC50: 2.45E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235634BDBM235634((E)-1-(2,4-dihydroxyphenyl)-3-(2-methoxyphenyl)-2-...)
Affinity DataIC50: 2.63E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 50140168BDBM50140168((E)-3,2'',4''-Trihydroxychalcone | CHEMBL1083821 |...)
Affinity DataIC50: 8.03E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 50360514BDBM50360514(CHEMBL1935203 | (E)-1-(2,4-dihydroxyphenyl)-3-(2-c...)
Affinity DataIC50: 1.14E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235640BDBM235640((E)-1-(3,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)
Affinity DataIC50: 1.18E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235639BDBM235639((E)-1-(2,6-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)
Affinity DataIC50: 1.56E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235641BDBM235641((E)-1-(3,5-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)
Affinity DataIC50: 1.94E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235638BDBM235638((E)-1-(2,3-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)
Affinity DataIC50: 2.18E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235636BDBM235636((E)-1-(3-hydroxyphenyl)-3-(2-hydroxyphenyl)-2-prop...)
Affinity DataIC50: 3.04E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 50042944BDBM50042944(cid_638278 | (E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hyd...)
Affinity DataIC50: 3.30E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 50027481BDBM50027481(CHEMBL3335589 | (E)-1-(2,5-dihydroxyphenyl)-3-(2-h...)
Affinity DataIC50: 4.18E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235637BDBM235637((E)-1-(4-hydroxyphenyl)-3-(2-hydroxyphenyl)-2-prop...)
Affinity DataIC50: 5.81E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 50027665BDBM50027665(CHEMBL3357534 | (E)-1-(2,4-dihydroxyphenyl)-3-(2-a...)
Affinity DataIC50: 6.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 50015607BDBM50015607(CHEMBL150755 | D-501 | (E)-1-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: 6.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 235635BDBM235635((E)-1-(2,4-dihydroxyphenyl)-3-(2-nitrophenyl)-2-pr...)
Affinity DataIC50: 6.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandChemical structure of BindingDB Monomer ID 86002BDBM86002(Chalcone, 1 | (E)-1-phenyl-3-(2-hydroxyphenyl)-2-p...)
Affinity DataIC50: 6.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed