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Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50033103
TargetL-lactate dehydrogenase A chain(Human)
Universita` Di Pisa

Curated by ChEMBL
LigandPNGBDBM50339607(1-Hydroxy-6-phenyl-4-trifluoromethyl-1H-indole-2-c...)
Affinity DataKi:  4.70E+3nMAssay Description:Competitive inhibition of human LDH-A using pyruvate as substrate after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetL-lactate dehydrogenase A chain(Human)
Universita` Di Pisa

Curated by ChEMBL
LigandPNGBDBM50066974(7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-naphthale...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of human LDH-A using pyruvate as substrate and NADH as cofactor at 125 uM after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetL-lactate dehydrogenase A chain(Human)
Universita` Di Pisa

Curated by ChEMBL
LigandPNGBDBM50339607(1-Hydroxy-6-phenyl-4-trifluoromethyl-1H-indole-2-c...)
Affinity DataKi:  8.90E+3nMAssay Description:Competitive inhibition of human LDH-A using NADH as substrate after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetL-lactate dehydrogenase A chain(Human)
Universita` Di Pisa

Curated by ChEMBL
LigandPNGBDBM50339605(1-Hydroxy-5-phenyl-1H-indole-2-carboxylic Acid | C...)
Affinity DataKi:  1.04E+4nMAssay Description:Competitive inhibition of human LDH-A using NADH as substrate after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetL-lactate dehydrogenase A chain(Human)
Universita` Di Pisa

Curated by ChEMBL
LigandPNGBDBM50339605(1-Hydroxy-5-phenyl-1H-indole-2-carboxylic Acid | C...)
Affinity DataKi:  1.57E+4nMAssay Description:Competitive inhibition of human LDH-A using pyruvate as substrate after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetL-lactate dehydrogenase A chain(Human)
Universita` Di Pisa

Curated by ChEMBL
LigandPNGBDBM50339606(1-Hydroxy-6-phenyl-1H-indole-2-carboxylic Acid | C...)
Affinity DataKi:  1.98E+4nMAssay Description:Competitive inhibition of human LDH-A using NADH as substrate after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetL-lactate dehydrogenase A chain(Human)
Universita` Di Pisa

Curated by ChEMBL
LigandPNGBDBM50339606(1-Hydroxy-6-phenyl-1H-indole-2-carboxylic Acid | C...)
Affinity DataKi:  3.54E+4nMAssay Description:Competitive inhibition of human LDH-A using pyruvate as substrate after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetL-lactate dehydrogenase A chain(Human)
Universita` Di Pisa

Curated by ChEMBL
LigandPNGBDBM23222(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Affinity DataKi:  1.38E+5nMAssay Description:Inhibition of human LDH-A using pyruvate as substrate and NADH as cofactor at 125 uM after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetL-lactate dehydrogenase A chain(Human)
Universita` Di Pisa

Curated by ChEMBL
LigandPNGBDBM23251(1,2,5-Thiadiazole, TDA1 | 4-hydroxy-1,2,5-thiadiaz...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human LDH-A using pyruvate as substrate and NADH as cofactor at 125 uM after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetL-lactate dehydrogenase A chain(Human)
Universita` Di Pisa

Curated by ChEMBL
LigandPNGBDBM23242(1,2(1,5)-Isoxazole, IOA1 | 3-hydroxy-1,2-oxazole-4...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human LDH-A using pyruvate as substrate and NADH as cofactor at 125 uM after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed