Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50033138
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)
Affinity DataIC50:  11nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM20933(3,6-dimethyl-4-(pentan-3-yloxy)-2-(2,4,6-trimethyl...)
Affinity DataIC50:  92nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340209(2-(dipropylamino)-3,7-dimethyl-5-(2,4,6-trimethylp...)
Affinity DataIC50:  120nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340211(2-(bis(cyclopropylmethyl)amino)-5-mesityl-3,7-dime...)
Affinity DataIC50:  140nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340210(2-(dibutylamino)-5-mesityl-3,7-dimethyl-3H-pyrrolo...)
Affinity DataIC50:  970nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340213(2-(dipropylamino)-5-mesityl-3,6,7-trimethyl-3H-pyr...)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340215(5-(2,4-dimethylphenyl)-2-(dipropylamino)-3,7-dimet...)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340218(5-(2,4-bis(trifluoromethyl)phenyl)-2-(dipropylamin...)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340217(5-(2,4-dimethoxyphenyl)-2-(dipropylamino)-3,7-dime...)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340216(2-(dipropylamino)-3,7-dimethyl-5-(2,4,6-trimethoxy...)
Affinity DataIC50:  3.10E+3nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340214(5-(2,4-dimethylphenyl)-2-(dipropylamino)-3,6,7-tri...)
Affinity DataIC50:  3.30E+3nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340212(5-mesityl-3,7-dimethyl-2-(piperidin-1-yl)-3H-pyrro...)
Affinity DataIC50:  3.80E+3nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340208(2-(diethylamino)-5-mesityl-3,7-dimethyl-3H-pyrrolo...)
Affinity DataIC50:  7.70E+3nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340219(4-chloro-5-mesityl-7-methyl-N,N-dipropyl-7H-pyrrol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonistic activity at human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340207(5-mesityl-4-methoxy-7-methyl-N,N-dipropyl-7H-pyrro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonistic activity at human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50340206(2-(dipropylamino)-5-mesityl-7-methyl-7H-pyrrolo[2,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonistic activity at human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed