Compile Data Set for Download or QSAR
Report error Found 68 Enz. Inhib. hit(s) with all data for entry = 50041927
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50386178(ONO-1714 | CHEMBL1800346)
Affinity DataKi:  1.86nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50386178(ONO-1714 | CHEMBL1800346)
Affinity DataKi:  18.6nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50124535(5-[(4'-amino-5',8'-difluoro-1H,1'H-spiro[piperidin...)
Affinity DataIC50: 37.1nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418856(CHEMBL1800534)
Affinity DataIC50: 38.9nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50091805(2-amino-4,6-dimethylpyridine | CHEMBL59925 | CHEMB...)
Affinity DataIC50: 44.7nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418855(CHEMBL1800533)
Affinity DataIC50: 55.0nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418844(CHEMBL1800347)
Affinity DataIC50: 70.8nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50: 81.3nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50091805(2-amino-4,6-dimethylpyridine | CHEMBL59925 | CHEMB...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418845(CHEMBL1800348)
Affinity DataIC50: 115nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418851(CHEMBL1800528)
Affinity DataIC50: 145nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418847(CHEMBL1800523)
Affinity DataIC50: 155nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418860(CHEMBL1800526)
Affinity DataIC50: 186nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418850(CHEMBL1800527)
Affinity DataIC50: 380nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418847(CHEMBL1800523)
Affinity DataIC50: 447nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418859(CHEMBL1800531)
Affinity DataIC50: 513nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418854(CHEMBL1800532)
Affinity DataIC50: 724nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50124535(5-[(4'-amino-5',8'-difluoro-1H,1'H-spiro[piperidin...)
Affinity DataIC50: 741nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418853(CHEMBL1800530)
Affinity DataIC50: 776nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418847(CHEMBL1800523)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418856(CHEMBL1800534)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418855(CHEMBL1800533)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418852(CHEMBL1800529)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418845(CHEMBL1800348)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50063300(l-NIL | CHEMBL1744034 | (L-N6-1-iminoethyl)lysine ...)
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418844(CHEMBL1800347)
Affinity DataIC50: 6.61E+3nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418860(CHEMBL1800526)
Affinity DataIC50: 8.32E+3nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418846(CHEMBL51478)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418852(CHEMBL1800529)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418854(CHEMBL1800532)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418856(CHEMBL1800534)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418851(CHEMBL1800528)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418850(CHEMBL1800527)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418846(CHEMBL51478)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418846(CHEMBL51478)
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418851(CHEMBL1800528)
Affinity DataIC50: 4.57E+4nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418857(CHEMBL1800349)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418845(CHEMBL1800348)
Affinity DataIC50: 5.37E+4nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418853(CHEMBL1800530)
Affinity DataIC50: 5.89E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50063300(l-NIL | CHEMBL1744034 | (L-N6-1-iminoethyl)lysine ...)
Affinity DataIC50: 6.17E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418854(CHEMBL1800532)
Affinity DataIC50: 6.61E+4nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418855(CHEMBL1800533)
Affinity DataIC50: 8.71E+4nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418860(CHEMBL1800526)
Affinity DataIC50: 8.71E+4nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50063300(l-NIL | CHEMBL1744034 | (L-N6-1-iminoethyl)lysine ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418843(CHEMBL1185460)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418858(CHEMBL1800524)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418858(CHEMBL1800524)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
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