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Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50034057
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356075(CHEMBL1911818)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356076(CHEMBL1911817)
Affinity DataIC50:  1nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356075(CHEMBL1911818)
Affinity DataIC50:  1nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356076(CHEMBL1911817)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356091(CHEMBL1911679)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356090(CHEMBL1911678)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356078(CHEMBL1911815)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356077(CHEMBL1911816)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356079(CHEMBL1911814)
Affinity DataIC50:  3nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356094(CHEMBL1911829)
Affinity DataIC50:  4nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356094(CHEMBL1911829)
Affinity DataIC50:  5nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356066(CHEMBL1911827)
Affinity DataIC50:  5nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356074(CHEMBL1911819)
Affinity DataIC50:  7nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356095(CHEMBL1911830)
Affinity DataIC50:  7nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356090(CHEMBL1911678)
Affinity DataIC50:  9nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356067(CHEMBL1911826)
Affinity DataIC50:  10nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356095(CHEMBL1911830)
Affinity DataIC50:  12nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356074(CHEMBL1911819)
Affinity DataIC50:  13nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356091(CHEMBL1911679)
Affinity DataIC50:  16nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356066(CHEMBL1911827)
Affinity DataIC50:  16nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356073(CHEMBL1911820)
Affinity DataIC50:  20nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356092(CHEMBL1911680)
Affinity DataIC50:  32nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356068(CHEMBL1911825)
Affinity DataIC50:  40nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356071(CHEMBL1911822)
Affinity DataIC50:  50nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356069(CHEMBL1911824)
Affinity DataIC50:  50nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356073(CHEMBL1911820)
Affinity DataIC50:  50nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356089(CHEMBL1911682)
Affinity DataIC50:  53nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356065(CHEMBL1911828)
Affinity DataIC50:  65nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50:  90nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356082(CHEMBL1911811)
Affinity DataIC50:  90nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356081(CHEMBL1911812)
Affinity DataIC50:  110nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356070(CHEMBL1911823)
Affinity DataIC50:  120nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356080(CHEMBL1911813)
Affinity DataIC50:  180nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356086(CHEMBL1911685)
Affinity DataIC50:  230nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356072(CHEMBL1911821)
Affinity DataIC50:  275nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356087(CHEMBL1911684)
Affinity DataIC50:  300nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356085(CHEMBL1911686)
Affinity DataIC50:  340nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356084(CHEMBL1911809)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356083(CHEMBL1911810)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356088(CHEMBL1911683)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356072(CHEMBL1911821)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidatative metabolism of testosterone after 45 mins by MS analysis in the p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356093(CHEMBL1911681)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356075(CHEMBL1911818)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidatative metabolism of testosterone after 45 mins by MS analysis in the p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356068(CHEMBL1911825)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidatative metabolism of testosterone after 45 mins by MS analysis in the p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356074(CHEMBL1911819)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidatative metabolism of testosterone after 45 mins by MS analysis in the p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356067(CHEMBL1911826)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidatative metabolism of testosterone after 45 mins by MS analysis in the p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356065(CHEMBL1911828)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidatative metabolism of testosterone after 45 mins by MS analysis in the p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356071(CHEMBL1911822)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidatative metabolism of testosterone after 45 mins by MS analysis in the p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356066(CHEMBL1911827)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidatative metabolism of testosterone after 45 mins by MS analysis in the p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356070(CHEMBL1911823)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidatative metabolism of testosterone after 45 mins by MS analysis in the p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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