Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50034057
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356075BDBM50356075(CHEMBL1911818)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356076BDBM50356076(CHEMBL1911817)
Affinity DataIC50: 1nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356075BDBM50356075(CHEMBL1911818)
Affinity DataIC50: 1nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356090BDBM50356090(CHEMBL1911678)
Affinity DataIC50: 2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356076BDBM50356076(CHEMBL1911817)
Affinity DataIC50: 2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356091BDBM50356091(CHEMBL1911679)
Affinity DataIC50: 2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356078BDBM50356078(CHEMBL1911815)
Affinity DataIC50: 2nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356077BDBM50356077(CHEMBL1911816)
Affinity DataIC50: 2nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356079BDBM50356079(CHEMBL1911814)
Affinity DataIC50: 3nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356094BDBM50356094(CHEMBL1911829)
Affinity DataIC50: 4nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356094BDBM50356094(CHEMBL1911829)
Affinity DataIC50: 5nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356066BDBM50356066(CHEMBL1911827)
Affinity DataIC50: 5nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356074BDBM50356074(CHEMBL1911819)
Affinity DataIC50: 7nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356095BDBM50356095(CHEMBL1911830)
Affinity DataIC50: 7nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356090BDBM50356090(CHEMBL1911678)
Affinity DataIC50: 9nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356067BDBM50356067(CHEMBL1911826)
Affinity DataIC50: 10nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356095BDBM50356095(CHEMBL1911830)
Affinity DataIC50: 12nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356074BDBM50356074(CHEMBL1911819)
Affinity DataIC50: 13nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356066BDBM50356066(CHEMBL1911827)
Affinity DataIC50: 16nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356091BDBM50356091(CHEMBL1911679)
Affinity DataIC50: 16nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356073BDBM50356073(CHEMBL1911820)
Affinity DataIC50: 20nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356092BDBM50356092(CHEMBL1911680)
Affinity DataIC50: 32nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356068BDBM50356068(CHEMBL1911825)
Affinity DataIC50: 40nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356073BDBM50356073(CHEMBL1911820)
Affinity DataIC50: 50nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356071BDBM50356071(CHEMBL1911822)
Affinity DataIC50: 50nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356069BDBM50356069(CHEMBL1911824)
Affinity DataIC50: 50nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356089BDBM50356089(CHEMBL1911682)
Affinity DataIC50: 53nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356065BDBM50356065(CHEMBL1911828)
Affinity DataIC50: 65nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356082BDBM50356082(CHEMBL1911811)
Affinity DataIC50: 90nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299749BDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50: 90nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356081BDBM50356081(CHEMBL1911812)
Affinity DataIC50: 110nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356070BDBM50356070(CHEMBL1911823)
Affinity DataIC50: 120nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356080BDBM50356080(CHEMBL1911813)
Affinity DataIC50: 180nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356086BDBM50356086(CHEMBL1911685)
Affinity DataIC50: 230nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356072BDBM50356072(CHEMBL1911821)
Affinity DataIC50: 275nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356087BDBM50356087(CHEMBL1911684)
Affinity DataIC50: 300nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356085BDBM50356085(CHEMBL1911686)
Affinity DataIC50: 340nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356084BDBM50356084(CHEMBL1911809)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356083BDBM50356083(CHEMBL1911810)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356088BDBM50356088(CHEMBL1911683)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356072BDBM50356072(CHEMBL1911821)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidative metabolism of testosterone after 45 mins by MS analysis in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356093BDBM50356093(CHEMBL1911681)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356075BDBM50356075(CHEMBL1911818)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidative metabolism of testosterone after 45 mins by MS analysis in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356068BDBM50356068(CHEMBL1911825)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidative metabolism of testosterone after 45 mins by MS analysis in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356074BDBM50356074(CHEMBL1911819)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidative metabolism of testosterone after 45 mins by MS analysis in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356067BDBM50356067(CHEMBL1911826)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidative metabolism of testosterone after 45 mins by MS analysis in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356065BDBM50356065(CHEMBL1911828)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidative metabolism of testosterone after 45 mins by MS analysis in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356071BDBM50356071(CHEMBL1911822)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidative metabolism of testosterone after 45 mins by MS analysis in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356066BDBM50356066(CHEMBL1911827)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidative metabolism of testosterone after 45 mins by MS analysis in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356070BDBM50356070(CHEMBL1911823)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidative metabolism of testosterone after 45 mins by MS analysis in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
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