Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50040288
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391953BDBM50391953(CHEMBL2152288)
Affinity DataIC50: 1.67nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391978BDBM50391978(CHEMBL2152287)
Affinity DataIC50: 2.97nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391977BDBM50391977(CHEMBL2152286)
Affinity DataIC50: 4.62nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391950BDBM50391950(CHEMBL2152289)
Affinity DataIC50: 5.41nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391974BDBM50391974(CHEMBL2152283)
Affinity DataIC50: 8.36nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391976BDBM50391976(CHEMBL2152285)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391973BDBM50391973(CHEMBL2152282)
Affinity DataIC50: 13.6nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391955BDBM50391955(CHEMBL2152264)
Affinity DataKd:  16nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391971BDBM50391971(CHEMBL2152280)
Affinity DataIC50: 18.6nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391968BDBM50391968(CHEMBL2152277)
Affinity DataIC50: 22.2nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391963BDBM50391963(CHEMBL2152272)
Affinity DataIC50: 22.7nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391965BDBM50391965(CHEMBL2152274)
Affinity DataIC50: 25.0nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391962BDBM50391962(CHEMBL2152271)
Affinity DataIC50: 26.5nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391961BDBM50391961(CHEMBL2152270)
Affinity DataIC50: 31.4nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391966BDBM50391966(CHEMBL2152275)
Affinity DataIC50: 33.2nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391975BDBM50391975(CHEMBL2152284)
Affinity DataIC50: 33.8nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391964BDBM50391964(CHEMBL2152273)
Affinity DataIC50: 34.3nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391955BDBM50391955(CHEMBL2152264)
Affinity DataIC50: 42.7nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391970BDBM50391970(CHEMBL2152279)
Affinity DataIC50: 47nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332012BDBM50332012(N-(5-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataKd:  48nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391967BDBM50391967(CHEMBL2152276)
Affinity DataIC50: 53.7nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332019BDBM50332019(5-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridi...)
Affinity DataKd:  58nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391972BDBM50391972(CHEMBL2152281)
Affinity DataIC50: 64.7nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391960BDBM50391960(CHEMBL2152269)
Affinity DataIC50: 69.6nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391956BDBM50391956(CHEMBL2152265)
Affinity DataKd:  75nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391957BDBM50391957(CHEMBL2152266)
Affinity DataKd:  88nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391969BDBM50391969(CHEMBL2152278)
Affinity DataIC50: 88.6nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332020BDBM50332020(N-(3-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataKd:  91nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391959BDBM50391959(CHEMBL2152268)
Affinity DataKd:  110nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391951BDBM50391951(CHEMBL2152290)
Affinity DataIC50: 110nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391954BDBM50391954(CHEMBL2152262)
Affinity DataKd:  125nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332012BDBM50332012(N-(5-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataKd:  145nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391953BDBM50391953(CHEMBL2152288)
Affinity DataIC50: 145nMAssay Description:Inhibition of KIT by high throughput binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391958BDBM50391958(CHEMBL2152267)
Affinity DataKd:  270nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332019BDBM50332019(5-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridi...)
Affinity DataKd:  960nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332020BDBM50332020(N-(3-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataKd:  2.30E+3nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391955BDBM50391955(CHEMBL2152264)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391952BDBM50391952(CHEMBL2152291)
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391956BDBM50391956(CHEMBL2152265)
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391959BDBM50391959(CHEMBL2152268)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed