Compile Data Set for Download or QSAR
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Found 16 Enz. Inhib. hit(s) with all data for entry = 8368
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243079(17-Oxaandrost-5-ene-3β-yl-p-fluorobenzoate (2...)
Affinity DataIC50:  3.58nMAssay Description:The activity of the isozyme 5α-R type 2 was assayed as previously described [Hirosumi et al., J. Steroid Biochem. Mol. Biol., 52:357-363; Bratoe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  8.5nMAssay Description:The activity of the isozyme 5α-R type 2 was assayed as previously described [Hirosumi et al., J. Steroid Biochem. Mol. Biol., 52:357-363; Bratoe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243088(17-Chloro-16-formylandrost-5,16-diene-3β-yl-p...)
Affinity DataIC50:  550nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  630nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243084(17-Chloro-16-formylandrost-5,16-diene-3β-yl-b...)
Affinity DataIC50:  650nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243085(17-Chloro-16-formylandrost-5,16-diene-3β-yl-p...)
Affinity DataIC50:  700nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243081(17-Oxaandrost-5-ene-3β-yl-p-bromobenzoate (4))
Affinity DataIC50:  800nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243087(17-Chloro-16-formylandros-5,16-diene-3β-yl-p-...)
Affinity DataIC50:  800nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243082(17-Oxaandrost-5-ene-3β-yl-p-iodobenzoate (5))
Affinity DataIC50:  800nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243086(17-Chloro-16-formylandrost-5,16-diene-3β-yl-p...)
Affinity DataIC50:  900nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243089(17-Chloro-16-formylandrost-5,16-diene-3β-yl-p...)
Affinity DataIC50:  900nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243079(17-Oxaandrost-5-ene-3β-yl-p-fluorobenzoate (2...)
Affinity DataIC50:  900nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243078(17-Oxaandrost-5-ene-3β-yl-benzoate (1))
Affinity DataIC50:  1.00E+3nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243083(17-Oxaandrost-5-ene-3β−yl-p-methylbenzo...)
Affinity DataIC50:  5.00E+3nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243080(17-Oxaandrost-5-ene-3β-yl-p-chlorobenzoate (3...)
Affinity DataIC50:  5.00E+3nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
National University of Mexico City

LigandPNGBDBM243078(17-Oxaandrost-5-ene-3β-yl-benzoate (1))
Affinity DataIC50: >1.00E+5nMAssay Description:The activity of the isozyme 5α-R type 2 was assayed as previously described [Hirosumi et al., J. Steroid Biochem. Mol. Biol., 52:357-363; Bratoe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed