Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50040769
TargetTGF-beta receptor type-1(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21492BDBM21492(4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline | CH...)
Affinity DataIC50: 40nMAssay Description:Inhibition of TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110208BDBM50110208(SB-431542 | cid_4521392 | 4-(5-(benzo[d][1,3]dioxo...)
Affinity DataIC50: 66nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110208BDBM50110208(SB-431542 | cid_4521392 | 4-(5-(benzo[d][1,3]dioxo...)
Affinity DataIC50: 66nMAssay Description:Inhibition of TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399831BDBM50399831(CHEMBL2180266)
Affinity DataIC50: 170nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399830BDBM50399830(CHEMBL2180267)
Affinity DataIC50: 170nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399828BDBM50399828(CHEMBL2180268)
Affinity DataIC50: 400nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399828BDBM50399828(CHEMBL2180268)
Affinity DataIC50: 400nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399829BDBM50399829(CHEMBL2180273)
Affinity DataIC50: 460nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399829BDBM50399829(CHEMBL2180273)
Affinity DataIC50: 460nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399842BDBM50399842(CHEMBL2180281)
Affinity DataIC50: 530nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399861BDBM50399861(CHEMBL2180618)
Affinity DataIC50: 560nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399834BDBM50399834(CHEMBL2180270)
Affinity DataIC50: 590nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399860BDBM50399860(CHEMBL2180287)
Affinity DataIC50: 590nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399852BDBM50399852(CHEMBL2180612)
Affinity DataIC50: 730nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399843BDBM50399843(CHEMBL2180280)
Affinity DataIC50: 760nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399836BDBM50399836(CHEMBL2177136)
Affinity DataIC50: 790nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399838BDBM50399838(CHEMBL2180285)
Affinity DataIC50: 830nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399840BDBM50399840(CHEMBL2180283)
Affinity DataIC50: 830nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399853BDBM50399853(CHEMBL2180611)
Affinity DataIC50: 860nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399850BDBM50399850(CHEMBL2180614)
Affinity DataIC50: 890nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399835BDBM50399835(CHEMBL2180269)
Affinity DataIC50: 940nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399854BDBM50399854(CHEMBL2180610)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399841BDBM50399841(CHEMBL2180282)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399859BDBM50399859(CHEMBL2180288)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399851BDBM50399851(CHEMBL2180613)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399855BDBM50399855(CHEMBL2180609)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399833BDBM50399833(CHEMBL2180271)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399827BDBM50399827(CHEMBL2180274)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399827BDBM50399827(CHEMBL2180274)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399849BDBM50399849(CHEMBL2180615)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399827BDBM50399827(CHEMBL2180274)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399837BDBM50399837(CHEMBL2180286)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399857BDBM50399857(CHEMBL2180290)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399832BDBM50399832(CHEMBL2180272)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399828BDBM50399828(CHEMBL2180268)
Affinity DataIC50: 4.05E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399856BDBM50399856(CHEMBL2180608)
Affinity DataIC50: 4.05E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399839BDBM50399839(CHEMBL2180284)
Affinity DataIC50: 4.06E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399829BDBM50399829(CHEMBL2180273)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399858BDBM50399858(CHEMBL2180289)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399847BDBM50399847(CHEMBL2180276)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399862BDBM50399862(CHEMBL2180617)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399846BDBM50399846(CHEMBL2180277)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399848BDBM50399848(CHEMBL2180275)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399863BDBM50399863(CHEMBL2180616)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399844BDBM50399844(CHEMBL2180279)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399845BDBM50399845(CHEMBL2180278)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed