Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50040965
TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402996(CHEMBL2207440)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402999(CHEMBL2207441)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403004(CHEMBL2207439)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403003(CHEMBL2207823)
Affinity DataIC50:  31nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402991(CHEMBL2207428)
Affinity DataIC50:  57nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402999(CHEMBL2207441)
Affinity DataIC50:  62nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403001(CHEMBL2207438)
Affinity DataIC50:  69nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403002(CHEMBL2207430)
Affinity DataIC50:  75nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402990(CHEMBL2207427)
Affinity DataIC50:  78nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402996(CHEMBL2207440)
Affinity DataIC50:  98nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403007(CHEMBL2207435)
Affinity DataIC50:  141nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403006(CHEMBL2207821)
Affinity DataIC50:  173nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318872(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-((...)
Affinity DataIC50:  190nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB


TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403005(CHEMBL2207822)
Affinity DataIC50:  225nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403004(CHEMBL2207439)
Affinity DataIC50:  236nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403003(CHEMBL2207823)
Affinity DataIC50:  265nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403002(CHEMBL2207430)
Affinity DataIC50:  283nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403001(CHEMBL2207438)
Affinity DataIC50:  328nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402998(CHEMBL2207433)
Affinity DataIC50:  361nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402997(CHEMBL2207429)
Affinity DataIC50:  398nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403000(CHEMBL2207437)
Affinity DataIC50:  429nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402999(CHEMBL2207441)
Affinity DataIC50:  473nMAssay Description:Inhibition of FAK after 2hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402998(CHEMBL2207433)
Affinity DataIC50:  524nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402990(CHEMBL2207427)
Affinity DataIC50:  530nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402997(CHEMBL2207429)
Affinity DataIC50:  553nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402993(CHEMBL2207432)
Affinity DataIC50:  607nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402996(CHEMBL2207440)
Affinity DataIC50:  608nMAssay Description:Inhibition of FAK after 2hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318872(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-((...)
Affinity DataIC50:  637nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402992(CHEMBL2207431)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402995(CHEMBL2207436)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402994(CHEMBL2207426)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403000(CHEMBL2207437)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402994(CHEMBL2207426)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402995(CHEMBL2207436)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402993(CHEMBL2207432)
Affinity DataIC50:  3.82E+3nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403007(CHEMBL2207435)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402992(CHEMBL2207431)
Affinity DataIC50:  4.77E+3nMAssay Description:Inhibition of FAK after 2hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402991(CHEMBL2207428)
Affinity DataIC50:  7.66E+3nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402990(CHEMBL2207427)
Affinity DataIC50:  7.86E+3nMAssay Description:Inhibition of FAK after 2hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318872(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-((...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK after 2hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402993(CHEMBL2207432)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK after 2hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403002(CHEMBL2207430)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK after 2hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402997(CHEMBL2207429)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK after 2hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403008(CHEMBL2207434)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403009(CHEMBL2207442)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed