Compile Data Set for Download or QSAR
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Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50042394
TargetPlatelet-derived growth factor receptor alpha(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425387(CHEMBL2311806)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  10nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiscoidin domain-containing receptor 2(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425387(CHEMBL2311806)
Affinity DataIC50:  17nMAssay Description:Inhibition of human DDR2 using KKSRGDYMTMQIG peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor alpha(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  26nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataIC50:  33nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425387(CHEMBL2311806)
Affinity DataIC50:  55nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor beta(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor alpha(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataIC50:  84nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataIC50:  108nMAssay Description:Inhibition of human LCK using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  118nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ABL1(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425387(CHEMBL2311806)
Affinity DataIC50:  136nMAssay Description:Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiscoidin domain-containing receptor 2(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  179nMAssay Description:Inhibition of human DDR2 using KKSRGDYMTMQIG peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiscoidin domain-containing receptor 2(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataIC50:  653nMAssay Description:Inhibition of human DDR2 using KKSRGDYMTMQIG peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ABL1(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  750nMAssay Description:Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor beta(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425387(CHEMBL2311806)
Affinity DataIC50:  768nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425387(CHEMBL2311806)
Affinity DataIC50:  882nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataIC50:  974nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lyn(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425387(CHEMBL2311806)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of human LCK using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ABL1(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lyn(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425387(CHEMBL2311806)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor beta(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataIC50:  9.55E+3nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of human LCK using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lyn(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor beta(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataIC50:  3.54E+4nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataIC50:  4.46E+4nMAssay Description:Inhibition of human LCK using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lyn(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataIC50:  4.54E+4nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ABL1(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataKd:  29nMAssay Description:Binding affinity to human ABL1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataKd:  4.40nMAssay Description:Binding affinity to human c-KitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor beta(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  8.5nMAssay Description:Binding affinity to human PDGFRbeataMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor alpha(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  24nMAssay Description:Binding affinity to human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  58nMAssay Description:Binding affinity to human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiscoidin domain-containing receptor 2(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  14nMAssay Description:Binding affinity to human DDR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiscoidin domain-containing receptor 2(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataKd:  320nMAssay Description:Binding affinity to human DDR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor alpha(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataKd:  14nMAssay Description:Binding affinity to human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor beta(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425386(CHEMBL2311808)
Affinity DataKd:  7.20nMAssay Description:Binding affinity to human PDGFRbeataMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor beta(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataKd:  16nMAssay Description:Binding affinity to human PDGFRbeataMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor alpha(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataKd:  74nMAssay Description:Binding affinity to human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataKd:  4.00E+4nMAssay Description:Binding affinity to human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiscoidin domain-containing receptor 2(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataKd:  6.20nMAssay Description:Binding affinity to human DDR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataKd:  17nMAssay Description:Binding affinity to human c-KitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ABL1(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataKd:  3.60nMAssay Description:Binding affinity to human ABL1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetTyrosine-protein kinase ABL1(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  9.40nMAssay Description:Binding affinity to human ABL1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425385(CHEMBL2311807)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to human c-KitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor beta(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425387(CHEMBL2311806)
Affinity DataKd:  12nMAssay Description:Binding affinity to human PDGFRbeataMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor alpha(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425387(CHEMBL2311806)
Affinity DataKd:  65nMAssay Description:Binding affinity to human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50425387(CHEMBL2311806)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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