Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50044204
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009054BDBM50009054(CHEMBL3237954)
Affinity DataEC50:  7.10nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075373BDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataEC50:  44nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009051BDBM50009051(CHEMBL3233062)
Affinity DataEC50:  300nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009053BDBM50009053(CHEMBL3237953)
Affinity DataEC50:  900nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009055BDBM50009055(CHEMBL3237955)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009050BDBM50009050(CHEMBL3237951)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009031BDBM50009031(CHEMBL3237950)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009052BDBM50009052(CHEMBL3237952)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009064BDBM50009064(CHEMBL3237961)
Affinity DataEC50:  1.09E+4nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009062BDBM50009062(CHEMBL3237960)
Affinity DataEC50:  1.15E+4nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81939BDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009056BDBM50009056(CHEMBL3237956)
Affinity DataEC50:  3.25E+4nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009065BDBM50009065(CHEMBL3237962)
Affinity DataEC50:  4.37E+4nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009058BDBM50009058(CHEMBL3237957)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009059BDBM50009059(CHEMBL3237958)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009060BDBM50009060(CHEMBL3237959)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of P-glycoprotein (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed