Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50004798
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485970(CHEMBL2180358)
Affinity DataIC50: 11nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485953(CHEMBL2180356)
Affinity DataIC50: 16nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50364031(CHEMBL1950434)
Affinity DataIC50: 29nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50364034(CHEMBL1950535)
Affinity DataIC50: 33nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485954(CHEMBL2179955)
Affinity DataIC50: 35nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485974(CHEMBL2180376)
Affinity DataIC50: 37nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485955(CHEMBL2179953)
Affinity DataIC50: 39nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485989(CHEMBL2179954)
Affinity DataIC50: 44nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485976(CHEMBL2180357)
Affinity DataIC50: 46nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485963(CHEMBL2180389)
Affinity DataIC50: 48nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485982(CHEMBL2180383)
Affinity DataIC50: 56nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485966(CHEMBL2180381)
Affinity DataIC50: 58nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50364032(CHEMBL1950433)
Affinity DataIC50: 58nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485979(CHEMBL2180363)
Affinity DataIC50: 73nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485967(CHEMBL2180380)
Affinity DataIC50: 75nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485965(CHEMBL2177137)
Affinity DataIC50: 76nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485958(CHEMBL2180369)
Affinity DataIC50: 80nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485990(CHEMBL2180386)
Affinity DataIC50: 83nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485973(CHEMBL2180375)
Affinity DataIC50: 87nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485985(CHEMBL2180367)
Affinity DataIC50: 100nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485988(CHEMBL2180364)
Affinity DataIC50: 120nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485981(CHEMBL2180388)
Affinity DataIC50: 130nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485951(CHEMBL2180385)
Affinity DataIC50: 140nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485964(CHEMBL2180387)
Affinity DataIC50: 210nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485975(CHEMBL2180377)
Affinity DataIC50: 230nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485983(CHEMBL2180384)
Affinity DataIC50: 250nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485971(CHEMBL2180368)
Affinity DataIC50: 300nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485968(CHEMBL2180379)
Affinity DataIC50: 400nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485961(CHEMBL2180362)
Affinity DataIC50: 530nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485956(CHEMBL2180372)
Affinity DataIC50: 820nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485972(CHEMBL2180359)
Affinity DataIC50: 1.10E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485986(CHEMBL2180374)
Affinity DataIC50: 1.50E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485960(CHEMBL2180365)
Affinity DataIC50: 1.90E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485952(CHEMBL2180361)
Affinity DataIC50: 2.50E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485980(CHEMBL2180360)
Affinity DataIC50: 3.10E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485959(CHEMBL2180366)
Affinity DataIC50: 3.30E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485977(CHEMBL2180373)
Affinity DataIC50: 3.70E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485984(CHEMBL2180382)
Affinity DataIC50: 5.40E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485978(CHEMBL2180370)
Affinity DataIC50: 6.40E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485962(CHEMBL2180391)
Affinity DataIC50: 6.70E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485987(CHEMBL2180390)
Affinity DataIC50: 9.00E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485969(CHEMBL2180378)
Affinity DataIC50: 1.33E+4nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485957(CHEMBL2180371)
Affinity DataIC50: 1.90E+4nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed