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Found 18 Enz. Inhib. hit(s) with all data for entry = 50046257
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102819(CHEMBL3339368)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of RON (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102824(CHEMBL3339359)
Affinity DataIC50:  4nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102823(CHEMBL3339356)
Affinity DataIC50:  5nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102820(CHEMBL3339354)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of c-KIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102821(CHEMBL3339353)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50:  29nMAssay Description:Inhibition of RON (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50:  45nMAssay Description:Inhibition of c-KIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50351728(CHEMBL1822590)
Affinity DataIC50:  54nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50:  390nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50:  560nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  2.99E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50102822(CHEMBL3339360)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed