Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50045591
TargetAcetyl-CoA carboxylase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50069756(CHEMBL3407547 | US11186587, Example ND-630 | US109...)
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibition of human recombinant His-tagged ACC2 assessed as malonyl-CoA levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50069756(CHEMBL3407547 | US11186587, Example ND-630 | US109...)
Affinity DataIC50: 2.60nMAssay Description:In vitro inhibition of human recombinant His-tagged ACC1 assessed as malonyl-CoA levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50: 11nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Rat)
Amgen

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50: 17nMAssay Description:Inhibition of rat recombinant ACC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Rat)
Amgen

Curated by ChEMBL
LigandPNGBDBM50314924(6,7-dimethyl-1'-(7-methyl-1H-indazole-5-carbonyl)s...)
Affinity DataIC50: 25nMAssay Description:Inhibition of rat recombinant ACC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50069758(CHEMBL3407543)
Affinity DataIC50: 50nMAssay Description:Inhibition of human ACC2 assessed as malonyl CoA formation by NADH-linked kinetic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50069760(CHEMBL3407541)
Affinity DataIC50: 60nMAssay Description:Inhibition of human ACC2 assessed as malonyl CoA formation by NADH-linked kinetic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50069759(CHEMBL3407542)
Affinity DataIC50: 80nMAssay Description:Inhibition of human ACC2 assessed as malonyl CoA formation by NADH-linked kinetic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM112919(US8623860, 1.33)
Affinity DataIC50: 180nMAssay Description:Inhibition of human ACC2 assessed as malonyl CoA formation by NADH-linked kinetic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50394658(CHEMBL2165411)
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro inhibition of human recombinant His-tagged ACC2 assessed as malonyl-CoA levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50069757(CHEMBL3407545)
Affinity DataIC50: 2.30E+4nMAssay Description:In vitro inhibition of human recombinant His-tagged ACC1 assessed as malonyl-CoA levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed