Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 50045377
LigandChemical structure of BindingDB Monomer ID 50059194BDBM50059194(CHEMBL3393337)
Affinity DataKi:  0.200nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059190BDBM50059190(CHEMBL3393333 | US20250032489, Compound GNE-3511)
Affinity DataKi: <0.5nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50059191BDBM50059191(CHEMBL3393334)
Affinity DataKi:  0.700nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059201BDBM50059201(CHEMBL3393329)
Affinity DataKi:  0.900nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059202BDBM50059202(CHEMBL3393327)
Affinity DataKi:  1nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059198BDBM50059198(CHEMBL3393340)
Affinity DataKi:  1nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059205BDBM50059205(CHEMBL3393322 | US9868720, No. 92)
Affinity DataKi:  2nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059211BDBM50059211(CHEMBL3393314)
Affinity DataKi:  4nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059200BDBM50059200(CHEMBL3393330)
Affinity DataKi:  5nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059189BDBM50059189(CHEMBL3393332)
Affinity DataKi:  5nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059207BDBM50059207(CHEMBL3393320)
Affinity DataKi:  7nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059206BDBM50059206(CHEMBL3393321)
Affinity DataKi:  7nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059192BDBM50059192(CHEMBL3393335)
Affinity DataKi:  8nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059193BDBM50059193(CHEMBL3393336)
Affinity DataKi:  8nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059199BDBM50059199(CHEMBL3393331)
Affinity DataKi:  14nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059210BDBM50059210(CHEMBL3393315)
Affinity DataKi:  18nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059197BDBM50059197(CHEMBL3393339)
Affinity DataKi:  18nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059212BDBM50059212(CHEMBL3393312)
Affinity DataKi:  24nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059215BDBM50059215(CHEMBL3393328)
Affinity DataKi:  25nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059190BDBM50059190(CHEMBL3393333 | US20250032489, Compound GNE-3511)
Affinity DataIC50: 30nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50059203BDBM50059203(CHEMBL3393324)
Affinity DataKi:  33nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059214BDBM50059214(CHEMBL3393308)
Affinity DataKi:  35nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059204BDBM50059204(CHEMBL3393323)
Affinity DataKi:  41nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059191BDBM50059191(CHEMBL3393334)
Affinity DataIC50: 57nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059208BDBM50059208(CHEMBL3393318)
Affinity DataKi:  57nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059198BDBM50059198(CHEMBL3393340)
Affinity DataIC50: 62nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059194BDBM50059194(CHEMBL3393337)
Affinity DataIC50: 64nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059190BDBM50059190(CHEMBL3393333 | US20250032489, Compound GNE-3511)
Affinity DataIC50: 68nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059202BDBM50059202(CHEMBL3393327)
Affinity DataIC50: 69nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059201BDBM50059201(CHEMBL3393329)
Affinity DataIC50: 70nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059200BDBM50059200(CHEMBL3393330)
Affinity DataIC50: 79nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059213BDBM50059213(CHEMBL3393310)
Affinity DataKi:  85nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059209BDBM50059209(CHEMBL3393317)
Affinity DataKi:  90nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059196BDBM50059196(CHEMBL3393338)
Affinity DataKi:  93nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059207BDBM50059207(CHEMBL3393320)
Affinity DataIC50: 109nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059189BDBM50059189(CHEMBL3393332)
Affinity DataIC50: 125nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059190BDBM50059190(CHEMBL3393333 | US20250032489, Compound GNE-3511)
Affinity DataIC50: 129nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059193BDBM50059193(CHEMBL3393336)
Affinity DataIC50: 141nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059226BDBM50059226(CHEMBL3393325)
Affinity DataKi:  166nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059199BDBM50059199(CHEMBL3393331)
Affinity DataIC50: 193nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059249BDBM50059249(CHEMBL3393313 | US9868720, No. 6)
Affinity DataKi:  195nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059197BDBM50059197(CHEMBL3393339)
Affinity DataIC50: 213nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059212BDBM50059212(CHEMBL3393312)
Affinity DataIC50: 229nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059192BDBM50059192(CHEMBL3393335)
Affinity DataIC50: 233nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059203BDBM50059203(CHEMBL3393324)
Affinity DataIC50: 300nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059190BDBM50059190(CHEMBL3393333 | US20250032489, Compound GNE-3511)
Affinity DataIC50: 364nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059257BDBM50059257(CHEMBL3393309 | US9868720, No. 5)
Affinity DataKi:  401nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059206BDBM50059206(CHEMBL3393321)
Affinity DataIC50: 408nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059205BDBM50059205(CHEMBL3393322 | US9868720, No. 92)
Affinity DataIC50: 410nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50059216BDBM50059216(CHEMBL3393326)
Affinity DataKi:  431nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
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