Compile Data Set for Download or QSAR
maximum 50k data
Found 90 Enz. Inhib. hit(s) with all data for entry = 50046477
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114564(CHEMBL3608378)
Affinity DataIC50:  80nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114565(CHEMBL3608855)
Affinity DataIC50:  180nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114427(CHEMBL3608361)
Affinity DataIC50:  220nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114425(CHEMBL3608359)
Affinity DataIC50:  240nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114426(CHEMBL3608360)
Affinity DataIC50:  290nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114563(CHEMBL3608377)
Affinity DataIC50:  300nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114428(Myrtucommulone H)
Affinity DataIC50:  300nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114430(CHEMBL3608363)
Affinity DataIC50:  390nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114420(CHEMBL3608858)
Affinity DataIC50:  430nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114420(CHEMBL3608858)
Affinity DataIC50:  460nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as formation of all-trans isomer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114425(CHEMBL3608359)
Affinity DataIC50:  460nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114422(CHEMBL3608860)
Affinity DataIC50:  480nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114551(CHEMBL3608367)
Affinity DataIC50:  490nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114560(CHEMBL3608374)
Affinity DataIC50:  570nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114567(Myrtucommulone F)
Affinity DataIC50:  600nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114552(CHEMBL3608368)
Affinity DataIC50:  610nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114431(CHEMBL3608364)
Affinity DataIC50:  640nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114421(CHEMBL3608859)
Affinity DataIC50:  650nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114427(CHEMBL3608361)
Affinity DataIC50:  660nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114566(CHEMBL3608856)
Affinity DataIC50:  680nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114554(CHEMBL3608370)
Affinity DataIC50:  680nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114420(CHEMBL3608858)
Affinity DataIC50:  690nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114419(CHEMBL3608857)
Affinity DataIC50:  730nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as formation of all-trans isomer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114419(CHEMBL3608857)
Affinity DataIC50:  810nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114562(CHEMBL3608376)
Affinity DataIC50:  810nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114429(CHEMBL3608362)
Affinity DataIC50:  820nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114426(CHEMBL3608360)
Affinity DataIC50:  970nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114551(CHEMBL3608367)
Affinity DataIC50:  980nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114423(MYRTUCOMMULONE A)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114556(CHEMBL3608372)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114421(CHEMBL3608859)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as formation of all-trans isomer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114552(CHEMBL3608368)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114428(Myrtucommulone H)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114565(CHEMBL3608855)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114419(CHEMBL3608857)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114564(CHEMBL3608378)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114430(CHEMBL3608363)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114550(CHEMBL3608366)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114549(CHEMBL3608365)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114564(CHEMBL3608378)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as formation of all-trans isomer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114422(CHEMBL3608860)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114423(MYRTUCOMMULONE A)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of 5-LO in ionomycin-stimulated human PMNL using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114431(CHEMBL3608364)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114421(CHEMBL3608859)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114557(CHEMBL3608373)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of mPGES-1 in microsomal membranes isolated from interleukin-1beta-stimulated human A549 cells using PGH2 as substrate assessed as PGE2 fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114550(CHEMBL3608366)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as formation of all-trans isomer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114427(CHEMBL3608361)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as formation of all-trans isomer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114560(CHEMBL3608374)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of 5-LO in ionophore A23187-stimulated human PMNL using arachidonic acid as substrate assessed as formation of LTB4, 5(S),12(S)-DiHETE, 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114554(CHEMBL3608370)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as formation of all-trans isomer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50114562(CHEMBL3608376)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as formation of all-trans isomer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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