Compile Data Set for Download or QSAR
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Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50046788
TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131064(CHEMBL3634182)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131059(CHEMBL575257)
Affinity DataEC50:  8.70E+3nMAssay Description:Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131063(CHEMBL3634183)
Affinity DataEC50:  500nMAssay Description:Inhibitory concentration against Cathepsin B activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131059(CHEMBL575257)
Affinity DataEC50:  130nMAssay Description:Inhibitory concentration against Cathepsin B activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131059(CHEMBL575257)
Affinity DataEC50:  8.70E+3nMAssay Description:Inhibitory concentration against interleukin-2 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131062(CHEMBL3634184)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibitory concentration against interleukin-2 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131063(CHEMBL3634183)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibitory concentration against interleukin-2 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131064(CHEMBL3634182)
Affinity DataEC50:  17nMAssay Description:Inhibitory concentration against interleukin-2 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50118230(5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADEN...)
Affinity DataEC50:  3.27E+4nMAssay Description:Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50368125(ADENOSINE DIPHOSPHATE | ADP)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataEC50:  6.70E+3nMAssay Description:Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131060(CHEMBL3634186)
Affinity DataEC50:  90nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131061(CHEMBL3634185)
Affinity DataEC50:  37nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131062(CHEMBL3634184)
Affinity DataEC50:  880nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131063(CHEMBL3634183)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131064(CHEMBL3634182)
Affinity DataEC50:  17nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131059(CHEMBL575257)
Affinity DataEC50:  130nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50118230(5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADEN...)
Affinity DataEC50:  1.27E+3nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50118242(((2R,3S,4R,5R)-5-(6-amino-2-(methylthio)-9H-purin-...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50368125(ADENOSINE DIPHOSPHATE | ADP)
Affinity DataEC50:  24nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataEC50:  850nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131060(CHEMBL3634186)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131061(CHEMBL3634185)
Affinity DataEC50:  900nMAssay Description:Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131062(CHEMBL3634184)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131063(CHEMBL3634183)
Affinity DataEC50:  500nMAssay Description:Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 11(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131064(CHEMBL3634182)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50131062(CHEMBL3634184)
Affinity DataEC50:  880nMAssay Description:Inhibitory concentration against Cathepsin B activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed