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Found 12 Enz. Inhib. hit(s) with all data for entry = 50046735
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  560nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  790nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50056999(CHEMBL56367 | nimesulide)
Affinity DataIC50:  1.92E+3nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50128688(CHEMBL3628727)
Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50056999(CHEMBL56367 | nimesulide)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50128691(CHEMBL3628630)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50128688(CHEMBL3628727)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50128691(CHEMBL3628630)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50128748(CHEMBL3628629)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50128748(CHEMBL3628629)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed