Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50047378
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8125BDBM8125(Darunavir (DRV) | CHEMBL1323 | (3R,3aS,6aR)-hexahy...)
Affinity DataKi:  0.00800nMAssay Description:Binding affinity to wild type HIV1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163737BDBM50163737(CHEMBL3799941)
Affinity DataKi:  1.70nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163737BDBM50163737(CHEMBL3799941)
Affinity DataKi:  1.70nMAssay Description:Inhibition of HIV1 protease after 48 hrs by micro-titer plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163750BDBM50163750(CHEMBL3797292)
Affinity DataKi:  4nMAssay Description:Inhibition of HIV1 protease after 48 hrs by micro-titer plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163737BDBM50163737(CHEMBL3799941)
Affinity DataIC50: 6nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163737BDBM50163737(CHEMBL3799941)
Affinity DataIC50: 6nMAssay Description:Inhibition of HIV1 protease after 48 hrs by micro-titer plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200943BDBM50200943(cyclopentyl (2S,3S)-3-[4-([4-(5-chloro-2-methylphe...)
Affinity DataKi:  8nMAssay Description:Inhibition of HIV1 protease after 48 hrs by micro-titer plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163750BDBM50163750(CHEMBL3797292)
Affinity DataIC50: 13nMAssay Description:Inhibition of HIV1 protease after 48 hrs by micro-titer plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163752BDBM50163752(CHEMBL3799500)
Affinity DataKi:  16nMAssay Description:Binding affinity to wild type HIV1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163751BDBM50163751(CHEMBL3799799)
Affinity DataIC50: 40nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155311BDBM50155311(CHEMBL3781301)
Affinity DataIC50: 92nMAssay Description:Antagonist activity against CXCR4 in in human MOLT4 cells assessed as inhibition of SDF1alpha -induced Ca2+ mobilization after 30 mins by FACS analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163751BDBM50163751(CHEMBL3799799)
Affinity DataIC50: 650nMAssay Description:Inhibition of human recombinant CCR5 encoding an HIV-1-longterminal-repeat-regulated beta-galactosidase reporter gene expressed in human HeLaP4 cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163738BDBM50163738(CHEMBL3799917)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163736BDBM50163736(CHEMBL3799805)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HIV1 integrase using DIG/biotin-tagged annealed U5 LTR sequence oligonucleotides as substrate after 2 hrs by 3-processing strand transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163734BDBM50163734(CHEMBL3780574)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163733BDBM50163733(CHEMBL3800610)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163732BDBM50163732(CHEMBL3797729)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163730BDBM50163730(CHEMBL3797258)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163729BDBM50163729(CHEMBL3800626)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163739BDBM50163739(CHEMBL3798397)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163742BDBM50163742(CHEMBL3797222)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163749BDBM50163749(CHEMBL3799880)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163740BDBM50163740(CHEMBL3800582)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163741BDBM50163741(CHEMBL3799995)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 protease using Pr SF-2-WTQ7K-Pr as substrate after 24 hrs by LC/MS-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163725BDBM50163725(CHEMBL3800276)
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of HIV1 subtype B proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163754BDBM50163754(CHEMBL1614842)
Affinity DataKd:  1.70E+5nMAssay Description:Binding affinity to HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163735BDBM50163735(CHEMBL1738817)
Affinity DataIC50: 2.95E+5nMAssay Description:Inhibition of HIV1 integrase using DIG/biotin-tagged annealed U5 LTR sequence oligonucleotides as substrate after 2 hrs by 3-processing strand transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163753BDBM50163753(CHEMBL1615094)
Affinity DataKd:  2.80E+6nMAssay Description:Binding affinity to HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 36291BDBM36291(sesamol)
Affinity DataKd:  5.50E+6nMAssay Description:Binding affinity to HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed