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Found 41 Enz. Inhib. hit(s) with all data for entry = 50047291
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158375(CHEMBL3781284)
Affinity DataIC50:  27nMAssay Description:Inhibition of GST-tagged CARM1 (unknown origin) using tritiated S-adenosylmethionine as substrate at 6 nM by methylation- based filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158100(CHEMBL1614812)
Affinity DataIC50:  30nMAssay Description:Inhibition of human PRMT4 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158097(CHEMBL3780701)
Affinity DataIC50:  200nMAssay Description:Inhibition of CARM1 (unknown origin) using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158097(CHEMBL3780701)
Affinity DataIC50:  200nMAssay Description:Inhibition of human PRMT4 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataIC50:  230nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human PRMT4 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CARM1 (unknown origin) using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human PRMT8 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158097(CHEMBL3780701)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158095(CHEMBL3780444)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CARM1 (unknown origin) using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158095(CHEMBL3780444)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human PRMT4 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158095(CHEMBL3780444)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158095(CHEMBL3780444)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human PRMT8 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human PRMT1 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158097(CHEMBL3780701)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human PRMT8 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human PRMT3 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of FLAG-tagged human PRMT6 expressed in HEK293 cells assessed as reduction in H3R2 global methylation incubated for 20 hrs by Western blot...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50145918(CHEMBL3763993)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158095(CHEMBL3780444)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human PRMT3 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158095(CHEMBL3780444)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of human PRMT1 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158369(CHEMBL3781561)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158097(CHEMBL3780701)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of human PRMT1 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158371(CHEMBL3780738)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158372(CHEMBL3779956)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158085(CHEMBL3781201)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158084(CHEMBL3780979)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50068109(CHEMBL3402235)
Affinity DataIC50:  1.04E+5nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158087(CHEMBL3781841)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of CARM1 (unknown origin) using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158087(CHEMBL3781841)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of human PRMT4 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158370(CHEMBL3780615)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158391(CHEMBL3781682)
Affinity DataIC50:  1.36E+5nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158389(CHEMBL3781603)
Affinity DataIC50:  1.46E+5nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158377(CHEMBL3781043)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158087(CHEMBL3781841)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human PRMT8 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158087(CHEMBL3781841)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158373(CHEMBL3781266)
Affinity DataIC50:  3.60E+5nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50027796(2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...)
Affinity DataIC50:  4.30E+5nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158097(CHEMBL3780701)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human PRMT3 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158087(CHEMBL3781841)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human PRMT3 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158087(CHEMBL3781841)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human PRMT1 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataKd:  970nMAssay Description:Binding affinity to Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells by ITC methodMore data for this Ligand-Target Pair