Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50047427
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166941BDBM50166941(CHEMBL3797606)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166942BDBM50166942(CHEMBL3798501)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166944BDBM50166944(CHEMBL3799864)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166949BDBM50166949(CHEMBL3798128)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166945BDBM50166945(CHEMBL3798887)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166950BDBM50166950(CHEMBL3799428)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166948BDBM50166948(CHEMBL3799255)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166946BDBM50166946(CHEMBL3800597)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 149410BDBM149410(US8975249, I-10 | US10434101, Compound I-10 | US11...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166943BDBM50166943(CHEMBL3797963)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166947BDBM50166947(CHEMBL3799138)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383274BDBM50383274(CHEMBL1229592 | US9670213, WZ4002 | US10167264, WZ...)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029668BDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383274BDBM50383274(CHEMBL1229592 | US9670213, WZ4002 | US10167264, WZ...)
Affinity DataIC50: 31nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166949BDBM50166949(CHEMBL3798128)
Affinity DataIC50: 39nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166950BDBM50166950(CHEMBL3799428)
Affinity DataIC50: 46nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166942BDBM50166942(CHEMBL3798501)
Affinity DataIC50: 88nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166946BDBM50166946(CHEMBL3800597)
Affinity DataIC50: 154nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166945BDBM50166945(CHEMBL3798887)
Affinity DataIC50: 174nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 149410BDBM149410(US8975249, I-10 | US10434101, Compound I-10 | US11...)
Affinity DataIC50: 200nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166948BDBM50166948(CHEMBL3799255)
Affinity DataIC50: 248nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166941BDBM50166941(CHEMBL3797606)
Affinity DataIC50: 272nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166944BDBM50166944(CHEMBL3799864)
Affinity DataIC50: 389nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029668BDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 409nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166947BDBM50166947(CHEMBL3799138)
Affinity DataIC50: 410nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166943BDBM50166943(CHEMBL3797963)
Affinity DataIC50: 731nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed