Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50048052
TargetSerine/threonine-protein kinase mTOR(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145416BDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr in presence of ATP by lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202550BDBM50202550(CHEMBL3905146)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145416BDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145416BDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202547BDBM50202547(CHEMBL3968925)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202618BDBM50202618(CHEMBL3896198)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202553BDBM50202553(CHEMBL3958024)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202547BDBM50202547(CHEMBL3968925)
Affinity DataIC50: 0.740nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202620BDBM50202620(CHEMBL3975939)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202555BDBM50202555(CHEMBL3897883)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202548BDBM50202548(CHEMBL3986709)
Affinity DataIC50: 0.910nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202624BDBM50202624(CHEMBL3985009)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202621BDBM50202621(CHEMBL3939972)
Affinity DataIC50: 1nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202550BDBM50202550(CHEMBL3905146)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202626BDBM50202626(CHEMBL3976938)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202554BDBM50202554(CHEMBL3904493)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202629BDBM50202629(CHEMBL3915419)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202628BDBM50202628(CHEMBL3978461)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202545BDBM50202545(CHEMBL3949358)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202550BDBM50202550(CHEMBL3905146)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202547BDBM50202547(CHEMBL3968925)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr in presence of ATP by lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202616BDBM50202616(CHEMBL3914319)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202549BDBM50202549(CHEMBL3951052)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145416BDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202623BDBM50202623(CHEMBL3942320)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202546BDBM50202546(CHEMBL3963018)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202627BDBM50202627(CHEMBL3924412)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202630BDBM50202630(CHEMBL3933347)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202552BDBM50202552(CHEMBL3895847)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202622BDBM50202622(CHEMBL3940597)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202546BDBM50202546(CHEMBL3963018)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202551BDBM50202551(CHEMBL3905930)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202625BDBM50202625(CHEMBL3896400)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202617BDBM50202617(CHEMBL3923330)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202547BDBM50202547(CHEMBL3968925)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202546BDBM50202546(CHEMBL3963018)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202619BDBM50202619(CHEMBL3925191)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202550BDBM50202550(CHEMBL3905146)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr in presence of ATP by lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202556BDBM50202556(CHEMBL3904794)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202560BDBM50202560(CHEMBL3905333)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145416BDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202547BDBM50202547(CHEMBL3968925)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202550BDBM50202550(CHEMBL3905146)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202546BDBM50202546(CHEMBL3963018)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202546BDBM50202546(CHEMBL3963018)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr in presence of ATP by lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202559BDBM50202559(CHEMBL3985191)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202631BDBM50202631(CHEMBL3911998)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25045BDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25045BDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr in presence of ATP by lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25045BDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2018
Entry Details Article
PubMed
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