Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50018899
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613700(CHEMBL1234303 | CHEBI:50226)
Affinity DataKd:  370nMAssay Description:Inhibition of m7GDP fluorescent probe binding to recombinant eIF4E (unknown origin) assessed as dissociation constant by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613700(CHEMBL1234303 | CHEBI:50226)
Affinity DataIC50: 720nMAssay Description:Inhibition of P32-[alpha-GTP] cap radiolabelled RNA binding to recombinant eIF4E (unknown origin) assessed as decrease in cross linked RNA-eIF4E comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613701(CHEMBL1232939 | CHEBI:17825)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of P32-[alpha-GTP] cap radiolabelled RNA binding to recombinant eIF4E (unknown origin) assessed as decrease in cross linked RNA-eIF4E comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613701(CHEMBL1232939 | CHEBI:17825)
Affinity DataKd:  3.90E+3nMAssay Description:Inhibition of m7GDP fluorescent probe binding to recombinant eIF4E (unknown origin) assessed as dissociation constant by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613702(CHEMBL5282449)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of P32-[alpha-GTP] cap radiolabelled RNA binding to recombinant eIF4E (unknown origin) assessed as decrease in cross linked RNA-eIF4E comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613703(CHEMBL5286550)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of P32-[alpha-GTP] cap radiolabelled RNA binding to recombinant eIF4E (unknown origin) assessed as decrease in cross linked RNA-eIF4E comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613704(CHEMBL5283082)
Affinity DataIC50: 3.86E+4nMAssay Description:Inhibition of P32-[alpha-GTP] cap radiolabelled RNA binding to recombinant eIF4E (unknown origin) assessed as decrease in cross linked RNA-eIF4E comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613702(CHEMBL5282449)
Affinity DataKd:  5.65E+4nMAssay Description:Inhibition of m7GDP fluorescent probe binding to recombinant eIF4E (unknown origin) assessed as dissociation constant by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613704(CHEMBL5283082)
Affinity DataKd:  5.78E+4nMAssay Description:Inhibition of m7GDP fluorescent probe binding to recombinant eIF4E (unknown origin) assessed as dissociation constant by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613703(CHEMBL5286550)
Affinity DataKd:  1.33E+5nMAssay Description:Inhibition of m7GDP fluorescent probe binding to recombinant eIF4E (unknown origin) assessed as dissociation constant by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed