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Report error Found 152 Enz. Inhib. hit(s) with all data for entry = 50048078
TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203953(CHEMBL3932562)
Affinity DataIC50:  0.00320nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50102750(CHEMBL3359091)
Affinity DataIC50:  0.00390nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

Target72 kDa type IV collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.0290nMAssay Description:Inhibition of recombinant human AMPA-activated MMP2 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204002(CHEMBL3889936)
Affinity DataIC50:  0.0510nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203961(CHEMBL3958969)
Affinity DataIC50:  0.0520nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203955(CHEMBL3978380)
Affinity DataIC50:  0.0710nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203958(CHEMBL3965628)
Affinity DataIC50:  0.0780nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.0970nMAssay Description:Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204006(CHEMBL3959990)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203956(CHEMBL3971135)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203963(CHEMBL3907881)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204007(CHEMBL3926071)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203954(CHEMBL3960062)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203962(CHEMBL3917494)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203953(CHEMBL3932562)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204005(CHEMBL3907007)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204002(CHEMBL3889936)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204009(CHEMBL3927817)
Affinity DataIC50:  0.360nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203957(CHEMBL3900916)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203961(CHEMBL3958969)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of recombinant human AMPA-activated MMP2 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204001(CHEMBL3894181)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203953(CHEMBL3932562)
Affinity DataIC50:  0.820nMAssay Description:Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203961(CHEMBL3958969)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204002(CHEMBL3889936)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203960(CHEMBL3892938)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203953(CHEMBL3932562)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant human AMPA-activated MMP3 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204008(CHEMBL3950850)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMacrophage metalloelastase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203961(CHEMBL3958969)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant human AMPA-activated MMP12 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203953(CHEMBL3932562)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant human AMPA-activated MMP2 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203956(CHEMBL3971135)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204002(CHEMBL3889936)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of recombinant human AMPA-activated MMP3 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203961(CHEMBL3958969)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant human AMPA-activated MMP3 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203961(CHEMBL3958969)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204002(CHEMBL3889936)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human AMPA-activated MMP2 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203953(CHEMBL3932562)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of recombinant human GST-tagged MMP14 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203953(CHEMBL3932562)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of recombinant human AMPA-activated MMP9 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204002(CHEMBL3889936)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of recombinant human AMPA-activated MMP9 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204002(CHEMBL3889936)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of recombinant human GST-tagged MMP14 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50025159(CHEMBL3337869)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetStromelysin-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrilysin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203953(CHEMBL3932562)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of recombinant human AMPA-activated MMP7 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMacrophage metalloelastase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203953(CHEMBL3932562)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of recombinant human AMPA-activated MMP12 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203956(CHEMBL3971135)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of recombinant human AMPA-activated MMP2 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMacrophage metalloelastase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204002(CHEMBL3889936)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of recombinant human AMPA-activated MMP12 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203956(CHEMBL3971135)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203963(CHEMBL3907881)
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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