Compile Data Set for Download or QSAR
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Found 23 Enz. Inhib. hit(s) with all data for entry = 50006648
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM66082((2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methy...)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501576(CHEMBL4071461)
Affinity DataIC50:  290nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501574(CHEMBL4062835)
Affinity DataIC50:  450nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501573(CHEMBL4090780)
Affinity DataIC50:  710nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501570(CHEMBL4095728)
Affinity DataIC50:  950nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501572(CHEMBL4061867)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501575(CHEMBL4098497)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50461757(CHEMBL4065674)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501568(CHEMBL4103483)
Affinity DataIC50:  2.48E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501567(CHEMBL4079226)
Affinity DataIC50:  2.55E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501571(CHEMBL4083636)
Affinity DataIC50:  2.84E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501557(CHEMBL4093938)
Affinity DataIC50:  3.19E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501565(CHEMBL4074287)
Affinity DataIC50:  3.61E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501566(CHEMBL4087099)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501564(CHEMBL4094791)
Affinity DataIC50:  4.13E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501563(CHEMBL4097295)
Affinity DataIC50:  4.34E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501560(CHEMBL4085240)
Affinity DataIC50:  4.78E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501558(CHEMBL4074984)
Affinity DataIC50:  5.28E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501556(CHEMBL4066381)
Affinity DataIC50:  5.33E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501562(CHEMBL4070083)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501561(CHEMBL4063614)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501569(CHEMBL4068381)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50501559(CHEMBL4101669)
Affinity DataIC50:  2.01E+4nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed