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Compile Data Set for Download or QSAR
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Found
50
Enz. Inhib. hit(s) with all data for entry = 4644
Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
((3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimet...)
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Affinity Data
Ki: 0.700nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50062261
(CHEMBL829 | Dimethyl-(2-methyl-3-phenothiazin-10-y...)
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Affinity Data
Ki: 1.30nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81472
(CAS_10646 | NSC_10646 | Pyrathiazine)
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Affinity Data
Ki: 1.5nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81464
(2-[(4-chlorophenyl)-(2-pyridyl)methoxy]ethyl-dimet...)
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Affinity Data
Ki: 2.30nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81470
(CAS_14677 | Methdilazine | NSC_14677 | US9504692, ...)
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Affinity Data
Ki: 2.30nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50017696
((2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiaz...)
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Affinity Data
Ki: 2.90nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50017721
(1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...)
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Affinity Data
Ki: 3.10nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50241333
(4-(benzhydryloxy)-1-methylpiperidine | CHEMBL1492 ...)
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Affinity Data
Ki: 3.20nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)
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Affinity Data
Ki: 4.10nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81469
(CAS_91-80-5 | Methapyrilene | NSC_4098)
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Affinity Data
Ki: 4.5nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM22567
(3H]pyrilamine | CHEMBL511 | Dorantamin | Mepyramin...)
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Affinity Data
Ki: 4.5nM
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PDB
3D Structure (crystal)
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50017666
(1-(p-bromophenyl)-1-(2-pyridyl)-3-dimethylaminopro...)
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Affinity Data
Ki: 4.70nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50292411
((E)-2-(3-(pyrrolidin-1-yl)-1-p-tolylprop-1-enyl)py...)
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Affinity Data
Ki: 5.60nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM35938
(1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpro...)
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Affinity Data
Ki: 8nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81452
(CAS_91533 | Dimethindene | NSC_91533)
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Affinity Data
Ki: 8nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50329371
(1-((4-chlorophenyl)(phenyl)methyl)-4-methylpiperaz...)
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Affinity Data
Ki: 9nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81465
(BROMODIPHENHYDRAMINE | Bromodiphen-hydramine | CAS...)
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Affinity Data
Ki: 13nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50017674
((2-Benzhydryloxy-ethyl)-dimethyl-amine | 2-(benzhy...)
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Affinity Data
Ki: 17nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50089147
(2-Methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1...)
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Affinity Data
Ki: 20nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
((Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethy...)
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Affinity Data
Ki: 20nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)
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Affinity Data
Ki: 26nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM78576
(CIS-THIOTHIXENE | MLS000028463 | SMR000058396 | TH...)
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Affinity Data
Ki: 27nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM67545
(N,N-dimethyl-3-(10-phenothiazinyl)-1-propanamine;h...)
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Affinity Data
Ki: 30nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81471
(CAS_91-81-6 | NSC_5587 | Tripelennamine)
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Affinity Data
Ki: 35nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
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Affinity Data
Ki: 36nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM112777
(NORTRIPTYLINE | US8629135, SW-02)
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Affinity Data
Ki: 46nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM67544
(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)
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Affinity Data
Ki: 52nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50176062
(3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-...)
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Affinity Data
Ki: 60nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]pro...)
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Affinity Data
Ki: 67nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81448
(CAS_5560-72-5 | IPRINDOLE | NSC_21722)
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Affinity Data
Ki: 100nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)
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Affinity Data
Ki: 182nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM35229
(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)
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Affinity Data
Ki: 250nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81467
(CAS_569-65-3 | CHEMBL1085765 | Meclizine | NSC_403...)
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Affinity Data
Ki: 250nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM76862
(ANTAZOLINE HYDROCHLORIDE | Antazoline | MLS0000285...)
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Affinity Data
Ki: 610nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
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Affinity Data
Ki: 670nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81466
(CAS_23095-76-3 | NSC_6445134 | l-Chlorpheniramine)
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Affinity Data
Ki: 700nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50008735
((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
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Affinity Data
Ki: 1.30E+3nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM21342
((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
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Affinity Data
Ki: 1.30E+3nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM86231
(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
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Affinity Data
Ki: 2.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 3.30E+3nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM22888
(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
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Affinity Data
Ki: >1.00E+4nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50015720
((hyoscine)3-Hydroxy-2-phenyl-propionic acid 9-meth...)
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Affinity Data
Ki: >1.00E+4nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM22883
(CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl...)
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Affinity Data
Ki: >1.00E+4nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50171269
(3-[2-(dimethylamino)ethyl]-1H-indol-4-yl dihydroge...)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM25878
(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM7966
(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
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Affinity Data
Ki: >1.00E+4nM
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81444
(CAS_185453 | NSC_185453 | WB 4101 | WB-4101)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81468
(CAS_34839-70-8 | Metiamide | NSC_1548992)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
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Target
Histamine H1 receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50031942
((6aR,9R)-4,6a,7-Trimethyl-4,6,6a,7,8,9-hexahydro-i...)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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