Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50000299
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245656(CHEMBL4059780)
Affinity DataIC50:  16nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245656(CHEMBL4059780)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245683(CHEMBL4064141)
Affinity DataIC50:  21nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245683(CHEMBL4064141)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245664(CHEMBL4068802)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  25nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245688(CHEMBL4083609)
Affinity DataIC50:  28nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245657(CHEMBL4101612)
Affinity DataIC50:  28nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245657(CHEMBL4101612)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245664(CHEMBL4068802)
Affinity DataIC50:  30nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245654(CHEMBL4063960)
Affinity DataIC50:  34nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245654(CHEMBL4063960)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245655(CHEMBL4091726)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245655(CHEMBL4091726)
Affinity DataIC50:  57nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245668(CHEMBL4083029)
Affinity DataIC50:  61nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245669(CHEMBL4077026)
Affinity DataIC50:  76nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245694(CHEMBL4101951)
Affinity DataIC50:  81nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245684(CHEMBL4085705)
Affinity DataIC50:  115nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245666(CHEMBL4083961)
Affinity DataIC50:  121nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245689(CHEMBL4093882)
Affinity DataIC50:  229nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245698(CHEMBL4072156)
Affinity DataIC50:  257nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245697(CHEMBL4077854)
Affinity DataIC50:  257nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245658(CHEMBL4090236)
Affinity DataIC50:  390nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245687(CHEMBL4091391)
Affinity DataIC50:  449nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245686(CHEMBL4063548)
Affinity DataIC50:  517nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245695(CHEMBL4072550)
Affinity DataIC50:  535nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245664(CHEMBL4068802)
Affinity DataIC50:  685nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245667(CHEMBL4099464)
Affinity DataIC50:  980nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245696(CHEMBL4061151)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245685(CHEMBL4099128)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245673(CHEMBL4102114)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245672(CHEMBL4078455)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245670(CHEMBL4072728)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245665(CHEMBL4096103)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245671(CHEMBL4074529)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 3A4(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245683(CHEMBL4064141)
Affinity DataIC50:  5.28E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245654(CHEMBL4063960)
Affinity DataIC50:  6.53E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245657(CHEMBL4101612)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245656(CHEMBL4059780)
Affinity DataIC50:  8.56E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245655(CHEMBL4091726)
Affinity DataIC50:  9.03E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed