Compile Data Set for Download or QSAR
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Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50000202
TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242325(CHEMBL4072295)
Affinity DataIC50:  42nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242347(CHEMBL4082777)
Affinity DataIC50:  82nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242340(CHEMBL4070657)
Affinity DataIC50:  105nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242326(CHEMBL4100766)
Affinity DataIC50:  142nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242332(CHEMBL4083770)
Affinity DataIC50:  216nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242341(CHEMBL4091553)
Affinity DataIC50:  439nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242358(CHEMBL4081270)
Affinity DataIC50:  655nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242327(CHEMBL4075048)
Affinity DataIC50:  763nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242330(CHEMBL4081818)
Affinity DataIC50:  764nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242329(CHEMBL4063829)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242342(CHEMBL4099289)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242343(CHEMBL4089137)
Affinity DataIC50:  3.92E+3nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242331(CHEMBL4062018)
Affinity DataIC50:  4.19E+3nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242344(CHEMBL4060952)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242350(CHEMBL4075783)
Affinity DataIC50:  3.93E+4nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242351(CHEMBL4074790)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGTPase KRas(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242328(CHEMBL4084139)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed