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Report error Found 70 Enz. Inhib. hit(s) with all data for entry = 50000217
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242631(CHEMBL4068366)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242631(CHEMBL4068366)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242631(CHEMBL4068366)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242631(CHEMBL4068366)
Affinity DataIC50:  224nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242654(CHEMBL4104503)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242654(CHEMBL4104503)
Affinity DataIC50:  234nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242653(CHEMBL4074448)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242653(CHEMBL4074448)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242653(CHEMBL4074448)
Affinity DataIC50:  275nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242653(CHEMBL4074448)
Affinity DataIC50:  275nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242660(CHEMBL4087082)
Affinity DataIC50:  363nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242657(CHEMBL4104938)
Affinity DataIC50:  370nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242660(CHEMBL4087082)
Affinity DataIC50:  370nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242657(CHEMBL4104938)
Affinity DataIC50:  372nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50:  407nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242654(CHEMBL4104503)
Affinity DataIC50:  447nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242654(CHEMBL4104503)
Affinity DataIC50:  450nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50:  501nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50:  510nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50:  520nMAssay Description:Inhibition of His6-tagged PARP15 (unknown origin) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50:  560nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50:  560nMAssay Description:Inhibition of His6-tagged PARP16 (unknown origin) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50:  562nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242655(CHEMBL4080281)
Affinity DataIC50:  650nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242655(CHEMBL4080281)
Affinity DataIC50:  676nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50:  690nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50:  692nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50:  700nMAssay Description:Inhibitory concentration against radioligand [3H](+)-NAN binding to haloperidol-sensitive sigma binding site in whole guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50:  708nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242626(CHEMBL4097232)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242626(CHEMBL4097232)
Affinity DataIC50:  813nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242660(CHEMBL4087082)
Affinity DataIC50:  891nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242631(CHEMBL4068366)
Affinity DataIC50:  900nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242660(CHEMBL4087082)
Affinity DataIC50:  900nMAssay Description:Inhibitory concentration against radioligand [3H](+)-NAN binding to haloperidol-sensitive sigma binding site in whole guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242631(CHEMBL4068366)
Affinity DataIC50:  977nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242633(CHEMBL4103623)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242633(CHEMBL4103623)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242665(CHEMBL4101019)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242665(CHEMBL4101019)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242663(CHEMBL4101188)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242663(CHEMBL4101188)
Affinity DataIC50:  2.24E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242652(CHEMBL4084742)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242652(CHEMBL4084742)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242658(CHEMBL4085694)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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