Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 17
TargetIsoform Beta of cGMP-dependent protein kinase 1 [1-351](Human)
Baylor College of Medicine

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  163nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2 [41-418,G356E](Human)
Baylor College of Medicine

LigandPNGBDBM65505(PET-cGMP)
Affinity DataEC50:  5.30nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIsoform Beta of cGMP-dependent protein kinase 1 [1-351](Human)
Baylor College of Medicine

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  212nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetIsoform Beta of cGMP-dependent protein kinase 1 [1-351](Human)
Baylor College of Medicine

LigandPNGBDBM65505(PET-cGMP)
Affinity DataEC50:  3.80nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  328nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65502(2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...)
Affinity DataEC50:  765nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  206nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65505(PET-cGMP)
Affinity DataEC50:  5.80nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  4.20nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65502(2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...)
Affinity DataEC50: <2nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  7.70nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65505(PET-cGMP)
Affinity DataEC50: <2nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  370nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65502(2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...)
Affinity DataEC50:  206nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  249nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM65505(PET-cGMP)
Affinity DataEC50:  18nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2(Human)
Baylor College of Medicine

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  257nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2(Human)
Baylor College of Medicine

LigandPNGBDBM65502(2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...)
Affinity DataEC50:  58nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2(Human)
Baylor College of Medicine

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  22nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2(Human)
Baylor College of Medicine

LigandPNGBDBM65505(PET-cGMP)
Affinity DataEC50:  225nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-dependent protein kinase 2 [41-418](Human)
Baylor College of Medicine

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  96nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2 [41-418](Human)
Baylor College of Medicine

LigandPNGBDBM65502(2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...)
Affinity DataEC50:  20nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2 [41-418](Human)
Baylor College of Medicine

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  5nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2 [41-418](Human)
Baylor College of Medicine

LigandPNGBDBM65505(PET-cGMP)
Affinity DataEC50:  193nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-dependent protein kinase 2 [41-418,G232E](Human)
Baylor College of Medicine

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  184nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2 [41-418,G232E](Human)
Baylor College of Medicine

LigandPNGBDBM65502(2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...)
Affinity DataEC50:  11nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2 [41-418,G232E](Human)
Baylor College of Medicine

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  116nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2 [41-418,G232E](Human)
Baylor College of Medicine

LigandPNGBDBM65505(PET-cGMP)
Affinity DataEC50:  1.96E+3nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-dependent protein kinase 2 [41-418,G356E](Human)
Baylor College of Medicine

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50:  50nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2 [41-418,G356E](Human)
Baylor College of Medicine

LigandPNGBDBM65502(2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...)
Affinity DataEC50:  30nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcGMP-dependent protein kinase 2 [41-418,G356E](Human)
Baylor College of Medicine

LigandPNGBDBM65501(8-pCP-cGMP | Cyclic GMP analogs | cGMP)
Affinity DataEC50: <1nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetIsoform Beta of cGMP-dependent protein kinase 1 [1-351](Human)
Baylor College of Medicine

LigandPNGBDBM65502(2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydrox...)
Affinity DataEC50:  222nMpH: 7.0Assay Description:Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)