Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50000189
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242179(CHEMBL4093459)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50322535(3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-meth...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242168(CHEMBL4101206)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242190(CHEMBL4103644)
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50345596(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242167(CHEMBL4076193)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242161(CHEMBL4097771)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242166(CHEMBL4085713)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242162(CHEMBL4070641)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242163(CHEMBL4092478)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242178(CHEMBL4077510)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242171(CHEMBL4074329)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242165(CHEMBL4100222)
Affinity DataIC50: 4nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242169(CHEMBL4075321)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50363397(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242183(CHEMBL4090058)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242160(CHEMBL4062017)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242180(CHEMBL4092506)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242182(CHEMBL4079252)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 16nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242185(CHEMBL4071683)
Affinity DataIC50: 100nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242170(CHEMBL4077028)
Affinity DataIC50: 121nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242181(CHEMBL4065711)
Affinity DataIC50: 184nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242172(CHEMBL4094827)
Affinity DataIC50: 231nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242164(CHEMBL4082210)
Affinity DataIC50: 240nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242176(CHEMBL4103510)
Affinity DataIC50: 556nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50242175(CHEMBL4087133)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of wild type KIT (unknown origin) using biotinylated poly-Glu-Tyr as substrate preincubated for 30 mins followed by substrate addition in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed