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Found 7 Enz. Inhib. hit(s) with all data for entry = 50000318
TargetCarbonic anhydrase 12(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  5.70nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  25nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50246196(CHEMBL4065195)
Affinity DataKi:  654nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50246196(CHEMBL4065195)
Affinity DataKi:  728nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50246204(CHEMBL4094756)
Affinity DataKi:  4.51E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50246204(CHEMBL4094756)
Affinity DataKi:  6.83E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50246196(CHEMBL4065195)
Affinity DataKd:  8.75E+5nMAssay Description:Binding affinity to human 15N-labeled MMP-12 catalytic domain (G106 to G263 residues) expressed in Escherichia coli BL21 Gold by 1H NSQC NMR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed