Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50002555
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17004BDBM17004([(3Z)-2-oxo-3-[1-(1H-pyrrol-2-yl)ethylidene]-2,3-d...)
Affinity DataIC50: 9nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103938BDBM103938(US8569511, 1)
Affinity DataEC50:  76nMAssay Description:Inhibition of PDK1 mediated PI3K/Akt/mTOR pathway activation in human AN3CA cells assessed as reduction in ribosomal p70S6 protein phosphorylation af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103939BDBM103939(US8569511, 2)
Affinity DataEC50:  77nMAssay Description:Inhibition of PDK1 mediated PI3K/Akt/mTOR pathway activation in human AN3CA cells assessed as reduction in ribosomal p70S6 protein phosphorylation af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103938BDBM103938(US8569511, 1)
Affinity DataIC50: 80nMAssay Description:Inhibition of PDK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103938BDBM103938(US8569511, 1)
Affinity DataIC50: 80nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103939BDBM103939(US8569511, 2)
Affinity DataIC50: 90nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103939BDBM103939(US8569511, 2)
Affinity DataIC50: 94nMAssay Description:Inhibition of PDK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103919BDBM103919(US8569511, 3)
Affinity DataIC50: 200nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103920BDBM103920(US8569511, 4)
Affinity DataIC50: 200nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103924BDBM103924(US8569511, 8)
Affinity DataIC50: 300nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103926BDBM103926(US8569511, 10)
Affinity DataIC50: 400nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103922BDBM103922(US8569511, 6)
Affinity DataIC50: 400nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103921BDBM103921(US8569511, 5)
Affinity DataIC50: 800nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103928BDBM103928(US8569511, 12)
Affinity DataIC50: 900nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103923BDBM103923(US8569511, 7)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103925BDBM103925(US8569511, 9)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459977BDBM50459977(CHEMBL4228611)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103929BDBM103929(US8569511, 13)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103927BDBM103927(US8569511, 11)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103934BDBM103934(US8569511, 18)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103930BDBM103930(US8569511, 14)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459976BDBM50459976(CHEMBL4226486)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103931BDBM103931(US8569511, 15)
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103935BDBM103935(US8569511, 19)
Affinity DataIC50: 5.39E+4nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254987BDBM50254987(6-bromo-1H-indazol-3-amine | CHEMBL501406)
Affinity DataIC50: 8.24E+4nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254986BDBM50254986(5-bromo-1H-indazol-3-amine | CHEMBL465091 | EN300-...)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Brigham Young University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459978BDBM50459978(CHEMBL4225389)
Affinity DataIC50: 1.64E+5nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed