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Found 72 Enz. Inhib. hit(s) with all data for entry = 50001570
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50:  7nMAssay Description:Inhibition of ROS1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50:  12nMAssay Description:Inhibition of ALK (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284508(CHEMBL4166182)
Affinity DataIC50:  370nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284518(CHEMBL4168903)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284436(CHEMBL4174101)
Affinity DataIC50:  440nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284437(CHEMBL4173409)
Affinity DataIC50:  440nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284519(CHEMBL4162738)
Affinity DataIC50:  570nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284517(CHEMBL4176767)
Affinity DataIC50:  640nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284493(CHEMBL4162098)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was evaluated for functional potency and efficacy at human Nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284515(CHEMBL4177227)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284519(CHEMBL4162738)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284514(CHEMBL4166604)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284496(CHEMBL4172265)
Affinity DataIC50:  1.80E+3nMAssay Description:Compound was evaluated for functional potencies and efficacies at human Nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284518(CHEMBL4168903)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284478(CHEMBL4165486)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284488(CHEMBL4160169)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284485(CHEMBL4170674)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284477(CHEMBL4168963)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284436(CHEMBL4174101)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284437(CHEMBL4173409)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284493(CHEMBL4162098)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284517(CHEMBL4176767)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284508(CHEMBL4166182)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284488(CHEMBL4160169)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284509(CHEMBL4171478)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284503(CHEMBL4170816)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284496(CHEMBL4172265)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284502(CHEMBL4162485)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284503(CHEMBL4170816)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284514(CHEMBL4166604)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284515(CHEMBL4177227)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284512(CHEMBL4170026)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284486(CHEMBL4165540)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284494(CHEMBL4170808)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284498(CHEMBL4175678)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284501(CHEMBL4159094)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284476(CHEMBL4168623)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284491(CHEMBL4176820)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284484(CHEMBL4163543)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284497(CHEMBL4161643)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284485(CHEMBL4170674)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284480(CHEMBL4170404)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284500(CHEMBL4165058)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284438(CHEMBL4177198)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284505(CHEMBL4174239)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284511(CHEMBL4173466)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284478(CHEMBL4165486)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284479(CHEMBL4169356)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284435(CHEMBL4166996)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284504(CHEMBL4160182)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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