Found 13 Enz. Inhib. hit(s) with all data for entry = 50002419 TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataKi: 9.90nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC8 (unknown origin) preincubated for 15 mins followed by acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin substrate addition and...More data for this Ligand-Target Pair
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC1/2 in human K562 nuclear extract using (QSY-7)-RGGRGLGK(Ac)-GGARRHRK(TAMRA)NH2 as substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human H1299 cells derived HDAC using biotin-labeled SGRGKGGKGLGKGGAKRHRKVLRD peracetylated with [3H]acetate at lysine residue as substr...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human H1299 cells derived HDAC using biotin-labeled SGRGKGGKGLGKGGAKRHRKVLRD peracetylated with [3H]acetate at lysine residue as substr...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract preincubated for 10 mins followed by Boc-Lys(acetyl)-AMC substrate addition measured after 30 mins b...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human H1299 cells derived HDAC using biotin-labeled SGRGKGGKGLGKGGAKRHRKVLRD peracetylated with [3H]acetate at lysine residue as substr...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Mazandaran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
