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Found 14 Enz. Inhib. hit(s) with all data for entry = 50002698
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM66082((2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methy...)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461747(CHEMBL4226361)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461754(CHEMBL4227213)
Affinity DataIC50:  590nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461758(CHEMBL4227155)
Affinity DataIC50:  610nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461750(CHEMBL4227367)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461748(CHEMBL4225586)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461757(CHEMBL4065674)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461755(CHEMBL4228675)
Affinity DataIC50:  2.53E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461756(CHEMBL4227478)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461751(CHEMBL4225877)
Affinity DataIC50:  7.93E+3nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461749(CHEMBL4226633)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461753(CHEMBL4228007)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461752(CHEMBL4227744)
Affinity DataIC50:  7.05E+4nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Perking University

Curated by ChEMBL
LigandPNGBDBM50461759(CHEMBL4229201)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolate as substrate after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed