Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50002763
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50188594(CHEMBL1086580 | CHEBI:62878 | US20240279201, Compo...)
Affinity DataKd:  4.20nMAssay Description:Binding affinity to recombinant human N-terminal His-tagged TNKS2 (Ser959 to Gly1166 residues) expressed in Escherichia coli by surface plasmon reson...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462628(CHEMBL4239155)
Affinity DataKd:  6.5nMAssay Description:Binding affinity to recombinant human N-terminal His-tagged TNKS2 (Ser959 to Gly1166 residues) expressed in Escherichia coli by surface plasmon reson...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462629(CHEMBL3594248)
Affinity DataKd:  19nMAssay Description:Binding affinity to recombinant human N-terminal His-tagged TNKS2 (Ser959 to Gly1166 residues) expressed in Escherichia coli by surface plasmon reson...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462627(CHEMBL1958308)
Affinity DataKd:  21nMAssay Description:Binding affinity to recombinant human N-terminal His-tagged TNKS2 (Ser959 to Gly1166 residues) expressed in Escherichia coli by surface plasmon reson...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462627(CHEMBL1958308)
Affinity DataKd:  520nMAssay Description:Binding affinity to recombinant human N-terminal GSt-tagged TNKS1 (1000 to 1328 residues) expressed in baculovirus infected Sf9 cells by surface plas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha/beta(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM11323(CHEMBL177820 | 4,5,6,7-tetrabromo-1H-1,2,3-benzotr...)
Affinity DataKd:  790nMAssay Description:Binding affinity to recombinant human CK2alpha/beta expressed in Escherichia coli by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462626(CHEMBL4127893)
Affinity DataKd:  1.25E+3nMAssay Description:Binding affinity to recombinant human PARP1 expressed in baculovirus infected Sf9 cells by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50462626(CHEMBL4127893)
Affinity DataKd:  5.26E+3nMAssay Description:Binding affinity to recombinant human N-terminal GSt-tagged TNKS1 (1000 to 1328 residues) expressed in baculovirus infected Sf9 cells by surface plas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed