Found 8 Enz. Inhib. hit(s) with all data for entry = 50012632 
Affinity DataIC50: 1.59E+3nMAssay Description:Covalent binding affinity to KRAS G12C mutant at Cys12 residue in human NCI-H358 cells assessed as reduction of log2 H/L ratio for tryptic peptide LV...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Covalent inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as loss of C12 tryptic peptide of KRAS G12C mutant measured after 6 hrs by L...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.80E+3nMAssay Description:Covalent binding affinity to KRAS G12C mutant at Cys12 residue in human NCI-H358 cells assessed as reduction of log2 H/L ratio for tryptic peptide LV...More data for this Ligand-Target Pair
TargetSynaptic vesicle membrane protein VAT-1 homolog(Homo sapiens)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.48E+3nMAssay Description:Covalent binding affinity to VAT1 at Cys residue in human NCI-H358 cells assessed as reduction of log2 H/L ratio for tryptic peptide ACGLNFADLMAR inc...More data for this Ligand-Target Pair
TargetSynaptic vesicle membrane protein VAT-1 homolog(Homo sapiens)
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.54E+3nMAssay Description:Covalent binding affinity to VAT1 at Cys residue in human NCI-H358 cells assessed as reduction of log2 H/L ratio for tryptic peptide CLVLTGFGGYDK inc...More data for this Ligand-Target Pair
Affinity DataIC50: 7.64E+3nMAssay Description:Covalent binding affinity to HMOX2 at Cys282 residue in human NCI-H358 cells assessed as reduction of log2 H/L ratio for tryptic peptide GALEGSSCPFR ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.44E+3nMAssay Description:Covalent binding affinity to CRYZ at Cys45 residue in human NCI-H358 cells assessed as reduction of log2 H/L ratio for tryptic peptide VHACGVNPVETYIR...More data for this Ligand-Target Pair
Affinity DataIC50: 1.46E+4nMAssay Description:Covalent binding affinity to RTN4 at Cys1101 residue in human NCI-H358 cells assessed as reduction of log2 H/L ratio for tryptic peptide YSNSALGHVNCT...More data for this Ligand-Target Pair
