Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50007250
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109086BDBM109086(US8604016, 670 | US9938267, Cmpd ID 670 | US107935...)
Affinity DataIC50: 5nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503291BDBM50503291(CHEMBL4562029)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant GAC (unknown origin) after 15 mins in presence of NADPH by glutamate oxidase coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 108715BDBM108715(US8604016, 295 | US9938267, Cmpd ID 295 | US107935...)
Affinity DataIC50: 57nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 108726BDBM108726(US8604016, 1038 | US9938267, Cmpd ID 1038)
Affinity DataIC50: 80nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507656BDBM50507656(CHEMBL4567806)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507659BDBM50507659(CHEMBL4451183)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507658BDBM50507658(CHEMBL4526782)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507655BDBM50507655(CHEMBL4445159)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507654BDBM50507654(CHEMBL4438668)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 404676BDBM404676(N-benzyl-1-{4-[5-(2- phenylacetamido)-1,3,4- thiad...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human GAC after 10 mins by glutamate oxidase coupled Amplex UltraRed dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507653BDBM50507653(CHEMBL4539656)
Affinity DataIC50: 100nMAssay Description:Inhibition of human GAC after 10 mins by glutamate oxidase coupled Amplex UltraRed dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507667BDBM50507667(CHEMBL4588102)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507651BDBM50507651(CHEMBL4534887)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507668BDBM50507668(CHEMBL4436826)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503307BDBM50503307(CHEMBL4466771)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507650BDBM50507650(CHEMBL4454765)
Affinity DataIC50: 100nMAssay Description:Inhibition of human GAC after 10 mins by glutamate oxidase coupled Amplex UltraRed dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507666BDBM50507666(CHEMBL4435601)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507665BDBM50507665(CHEMBL4450417)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507661BDBM50507661(CHEMBL4555453)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507662BDBM50507662(CHEMBL4583238)
Affinity DataIC50: 100nMAssay Description:Inhibition of human GAC after 10 mins by glutamate oxidase coupled Amplex UltraRed dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376126BDBM50376126(ERASTIN)
Affinity DataIC50: 140nMAssay Description:Inhibition of cystine/glutamate antiporter system xc- in human Calu1 cells assessed as reduction in L-[3,3'-14C]-cystine uptake in presence of Na+ fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103596BDBM50103596(CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...)
Affinity DataIC50: 160nMAssay Description:Inhibition of xCT-mediated cystein/glutamate transporter (unknown origin) assessed as reduction in L-[14C]cyctein uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376126BDBM50376126(ERASTIN)
Affinity DataIC50: 200nMAssay Description:Inhibition of cystine/glutamate antiporter system xc- in human HT1080 cells assessed as reduction in L-[3,3'-14C]-cystine uptake in presence of Na+ f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507657BDBM50507657(CHEMBL4574354)
Affinity DataIC50: 500nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507652BDBM50507652(CHEMBL4542082)
Affinity DataIC50: 500nMAssay Description:Inhibition of human GAC after 10 mins by glutamate oxidase coupled Amplex UltraRed dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507663BDBM50507663(CHEMBL4545450)
Affinity DataIC50: 500nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507664BDBM50507664(CHEMBL4452081)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507660BDBM50507660(CHEMBL4548854)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 108464BDBM108464(US8604016, 21 | US9938267, Cmpd ID 21)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeutral amino acid transporter B(0)(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140122BDBM50140122(CHEMBL3754053)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of ASCT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 47225BDBM47225(BDBM108725 | US8604016, 637 | US9938267, Cmpd ID 6...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355004BDBM50355004(CHEMBL1834956)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of xCT-mediated cystein/glutamate transporter (unknown origin) assessed as reduction in L-[14C]cyctein uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355002BDBM50355002(CHEMBL1834954)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of xCT-mediated cystein/glutamate transporter (unknown origin) assessed as reduction in L-[14C]cyctein uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103596BDBM50103596(CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...)
Affinity DataIC50: 4.50E+5nMAssay Description:Inhibition of cystine/glutamate antiporter system xc- in human HT1080 cells assessed as reduction in L-[3,3'-14C]-cystine uptake in presence of Na+ f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103596BDBM50103596(CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...)
Affinity DataIC50: 4.60E+5nMAssay Description:Inhibition of cystine/glutamate antiporter system xc- in human Calu1 cells assessed as reduction in L-[3,3'-14C]-cystine uptake in presence of Na+ fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355006BDBM50355006(CHEMBL1834958)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of xCT-mediated cystein/glutamate transporter (unknown origin) assessed as reduction in L-[14C]cyctein uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355008BDBM50355008(CHEMBL1834960)
Affinity DataIC50: 9.20E+5nMAssay Description:Inhibition of xCT-mediated cystein/glutamate transporter (unknown origin) assessed as reduction in L-[14C]cyctein uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeutral amino acid transporter B(0)(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088537BDBM50088537(CHEMBL6251 | US10189805, Compound 1)
Affinity DataIC50: 1.20E+6nMAssay Description:Inhibition of ASCT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed