Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50008300
TargetLa-related protein 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant P-TEFb expressed in baculovirus expression system after 10 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKi:  40nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetCyclin-dependent kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKi:  40nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKi:  40nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50263013(CHEMBL4079206)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human CDK9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50263013(CHEMBL4079206)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CDK4/cyclin D1 expressed in insect cells after 2.5 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK9/cyclin T (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) after 30 mins in presence of [gamma-33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50263013(CHEMBL4079206)
Affinity DataIC50:  23nMAssay Description:Inhibition of human CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  30nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin) in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetCyclin-dependent kinase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50263013(CHEMBL4079206)
Affinity DataIC50:  45nMAssay Description:Inhibition of human CDK6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50:  63nMAssay Description:Inhibition of human CDK4/cyclin D1 expressed in baculovirus expression system after 30 mins in presence of [gamma-33P]ATP by scintillation counting a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) using AAKAKKTPKKAKK-CONH2 as substrate after 20 mins by immunoprecipitation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CDK2/cyclinE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50193104(CHEMBL3905910)
Affinity DataIC50: <100nMAssay Description:Inhibition of human CDK6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50193104(CHEMBL3905910)
Affinity DataIC50: <100nMAssay Description:Inhibition of human CDK9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50193104(CHEMBL3905910)
Affinity DataIC50: <100nMAssay Description:Inhibition of human CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using AAKAKKTPKKAKK-CONH2 as substrate after 20 mins by immunoprecipitation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetCyclin-dependent kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50193104(CHEMBL3905910)
Affinity DataIC50: <100nMAssay Description:Inhibition of human CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5710((3S,4R)-2-[(2-Chlorophenyl)thio]-5,7-dihydroxy-8-(...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human GST-tagged CDK1/cyclin B1 expressed in baculovirus after 45 mins in presence of [gamma-33P]ATP by liquid scintillation counting a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  110nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5711((3S,4R)-2-(2-Chlorophenoxy)-5,7-dihydroxy-8-(3-hyd...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human GST-tagged CDK1/cyclin B1 expressed in baculovirus after 45 mins in presence of [gamma-33P]ATP by liquid scintillation counting a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50140257(5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one | 5...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged CDK9 (2 to 372 residues) expressed in baculovirus infected Sf9 insect cells co-expressing human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50189885(Rohitukine)
Affinity DataIC50:  300nMAssay Description:Inhibition of CDK9/cyclin T (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase pim-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCasein kinase II subunit alpha 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human recombinant CK2 expressed in Escherichia coli using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCasein kinase II subunit alpha 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human recombinant CK2 expressed in Escherichia coli using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCasein kinase II subunit alpha 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant CK2 expressed in Escherichia coli using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCasein kinase II subunit alpha 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  550nMAssay Description:Inhibition of human recombinant CK2 expressed in Escherichia coli using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase pim-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM26656(5,7,3,4,5-pentahydroxyflavone | 5,7-dihydroxy-2-(3...)
Affinity DataIC50:  650nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSerine/threonine-protein kinase pim-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  780nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCasein kinase II subunit alpha 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant CK2 expressed in Escherichia coli using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCasein kinase II subunit alpha 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant CK2 expressed in Escherichia coli using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50140257(5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one | 5...)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50517729(CHEMBL4454394)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human CDK2/cyclin E expressed in baculovirus expression system after 30 mins in presence of [gamma-33P]ATP by scintillation counting an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5710((3S,4R)-2-[(2-Chlorophenyl)thio]-5,7-dihydroxy-8-(...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human GST-tagged CDK2/cyclinE expressed in baculovirus after 45 mins in presence of [gamma-33P]ATP by liquid scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5711((3S,4R)-2-(2-Chlorophenoxy)-5,7-dihydroxy-8-(3-hyd...)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibition of human GST-tagged CDK2/cyclinE expressed in baculovirus after 45 mins in presence of [gamma-33P]ATP by liquid scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase pim-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  2.71E+3nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human CDK2/cyclin E expressed in baculovirus expression system after 30 mins in presence of [gamma-33P]ATP by scintillation counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetO94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of protein kinase C (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5711((3S,4R)-2-(2-Chlorophenoxy)-5,7-dihydroxy-8-(3-hyd...)
Affinity DataIC50:  6.15E+3nMAssay Description:Inhibition of human GST-tagged CDK4/cyclin D1 expressed in baculovirus after 1 hr in presence of [gamma-33P]ATP by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50189885(Rohitukine)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using AAKAKKTPKKAKK-CONH2 as substrate after 20 mins by immunoprecipitation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein kinase C zeta type(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of PKC in rat brain homogenate using FKKSFKL-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured after 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCasein kinase II subunit alpha 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human recombinant CK2 expressed in Escherichia coli using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCasein kinase II subunit alpha 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant CK2 expressed in Escherichia coli using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCasein kinase II subunit alpha 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant CK2 expressed in Escherichia coli using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50140257(5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one | 5...)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged and N-terminal GST-tagged CDK7/cyclinH/MAT1 expressed in baculovirus Sf21 insect c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Erk-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5710((3S,4R)-2-[(2-Chlorophenyl)thio]-5,7-dihydroxy-8-(...)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of human GST-tagged CDK4/cyclin D1 expressed in baculovirus after 1 hr in presence of [gamma-33P]ATP by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Displayed 1 to 50 (of 53 total ) | Next | Last >>
Jump to: